Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | BRD1 | O95696 | 1/20 | 0.38 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.38 |
| ▸ | BRPF3 | Q9ULD4 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | MOGAT2 | Q3SYC2 | 3/20 | 0.37 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4725656 | 0.90 | KMT2A (0.45) | DRD3LMNAMAPTBRD4BRPF1 | |
| SCHEMBL4726285 | 0.88 | PKM (0.48) | DRD3LMNAMAPTBRD4CNR2 | |
| SCHEMBL4727604 | 0.86 | MEN1 (0.47) | DRD3LMNAMAPTBRD4CNR2 | |
| SCHEMBL4779869 | 0.86 | SMN1; SMN2 (0.51) | GHSRLMNAMAPTBRD4PKM | |
| SCHEMBL4727679 | 0.84 | ALDH1A1 (0.48) | DRD3LMNAMAPTCNR2PKM | |
| SCHEMBL4727167 | 0.83 | DRD3 (0.45) | DRD3LMNAMAPTBRD4CNR2 | |
| SCHEMBL4729520 | 0.82 | MOGAT2 (0.44) | DRD3LMNABRD4CNR2MOGAT2 | |
| SCHEMBL4725451 | 0.82 | MAPT (0.53) | DRD3LMNAMAPTCA1CA2 | |
| SCHEMBL4728002 | 0.81 | MOGAT2 (0.45) | DRD3MAPTBRD4CNR2MOGAT2 | |
| SCHEMBL4728553 | 0.81 | ALPL (0.44) | DRD3LMNAPKMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008026046-A1 | MORPHOLINE D3 DOPAMINE ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-03-06 | — | — | WO | claimed |
| WO-2008026046-A1 | MORPHOLINE D3 DOPAMINE ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-03-06 | — | — | WO | disclosed |