Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 3/20 | 0.46 |
| ▸ | CNR2 | P34972 | 4/20 | 0.44 |
| ▸ | MOGAT2 | Q3SYC2 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.40 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.40 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4727167 | 0.88 | DRD3 (0.45) | LMNAMAPTDRD3CNR2MOGAT2 | |
| SCHEMBL4729815 | 0.88 | ALDH1A1 (0.47) | MEN1MAPTKMT2ADRD3CNR2 | |
| SCHEMBL4727679 | 0.88 | ALDH1A1 (0.48) | MEN1LMNAMAPTKMT2ADRD3 | |
| SCHEMBL4725656 | 0.88 | KMT2A (0.45) | MEN1LMNAMAPTKMT2ADRD3 | |
| SCHEMBL4729520 | 0.86 | MOGAT2 (0.44) | LMNADRD3CNR2MOGAT2PKM | |
| SCHEMBL4725665 | 0.86 | GHSR (0.44) | MEN1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4726285 | 0.86 | PKM (0.48) | MEN1LMNACYP3A4CYP2D6MAPT | |
| SCHEMBL4725658 | 0.86 | DRD3 (0.45) | MAPTDRD3CNR2MOGAT2TP53 | |
| SCHEMBL4726510 | 0.86 | CNR2 (0.49) | MEN1LMNAMAPTKMT2ADRD3 | |
| SCHEMBL4727964 | 0.83 | KDM2B (0.44) | DRD3CNR2MOGAT2MGAT2BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008026046-A1 | MORPHOLINE D3 DOPAMINE ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-03-06 | — | — | WO | claimed |
| WO-2008026046-A1 | MORPHOLINE D3 DOPAMINE ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-03-06 | — | — | WO | disclosed |