Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | UBE2N | P61088 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4725656 | 0.92 | KMT2A (0.45) | ALDH1A1HPGDLMNASMN1; SMN2PKM | |
| SCHEMBL4729520 | 0.90 | MOGAT2 (0.44) | LMNASMN1; SMN2PKMDRD3UBE2N | |
| SCHEMBL4728553 | 0.88 | ALPL (0.44) | ALDH1A1HPGDLMNASMN1; SMN2PKM | |
| SCHEMBL4727053 | 0.88 | LMNA (0.52) | ALDH1A1GAATSHRHPGDLMNA | |
| SCHEMBL4727604 | 0.88 | MEN1 (0.47) | ALDH1A1TSHRHPGDLMNAPKM | |
| SCHEMBL4726323 | 0.88 | MAPT (0.42) | ALDH1A1TSHRHPGDLMNASMN1; SMN2 | |
| SCHEMBL4725451 | 0.85 | MAPT (0.53) | ALDH1A1GAATSHRLMNASMN1; SMN2 | |
| SCHEMBL4725768 | 0.85 | MAPT (0.51) | ALDH1A1GAATSHRLMNASMN1; SMN2 | |
| SCHEMBL4726285 | 0.84 | PKM (0.48) | LMNASMN1; SMN2PKMDRD3TP53 | |
| SCHEMBL4725665 | 0.84 | GHSR (0.44) | LMNAPKMDRD3MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008026046-A1 | MORPHOLINE D3 DOPAMINE ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-03-06 | — | — | WO | claimed |
| WO-2008026046-A1 | MORPHOLINE D3 DOPAMINE ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-03-06 | — | — | WO | disclosed |