Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4727679 | 0.92 | ALDH1A1 (0.48) | KMT2ADRD3LMNAMAPTALDH1A1 | |
| SCHEMBL4726285 | 0.90 | PKM (0.48) | KMT2ADRD3LMNAMAPTBRD4 | |
| SCHEMBL4725665 | 0.90 | GHSR (0.44) | KMT2ADRD3LMNAMAPTBRD4 | |
| SCHEMBL4728553 | 0.88 | ALPL (0.44) | KMT2ADRD3LMNAALDH1A1PKM | |
| SCHEMBL4727604 | 0.88 | MEN1 (0.47) | KMT2ADRD3LMNAMAPTBRD4 | |
| SCHEMBL4725451 | 0.88 | MAPT (0.53) | KMT2ADRD3LMNAMAPTALDH1A1 | |
| SCHEMBL4726323 | 0.88 | MAPT (0.42) | KMT2ADRD3LMNAMAPTALDH1A1 | |
| SCHEMBL4727053 | 0.86 | LMNA (0.52) | KMT2ALMNAMAPTALDH1A1HTT | |
| SCHEMBL4725768 | 0.85 | MAPT (0.51) | KMT2ADRD3LMNAMAPTBRD4 | |
| SCHEMBL4729520 | 0.84 | MOGAT2 (0.44) | DRD3LMNABRD4PKMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008026046-A1 | MORPHOLINE D3 DOPAMINE ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-03-06 | — | — | WO | claimed |
| WO-2008026046-A1 | MORPHOLINE D3 DOPAMINE ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-03-06 | — | — | WO | disclosed |