Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 2/20 | 0.45 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
| ▸ | NNMT | P40261 | 1/20 | 0.39 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16739249 | 0.84 | HSD17B10 (0.46) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL4556902 | 0.84 | HSD17B10 (0.46) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL919063 | 0.84 | HSD17B10 (0.46) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL8708889 | 0.84 | HSD17B10 (0.46) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL35972 | 0.84 | HSD17B10 (0.46) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL35787 | 0.84 | HSD17B10 (0.46) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL5459284 | 0.84 | HSD17B10 (0.46) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL3427457 | 0.83 | ALDH1A1 (0.50) | ADRA1ALMNAALDH1A1KDM4EHPGD | |
| SCHEMBL3424668 | 0.83 | MAPT (0.50) | ADRA1AALDH1A1KDM4EHPGDHSD11B1 | |
| SCHEMBL1160668 | 0.82 | HSD17B10 (0.47) | KMT2AMEN1ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005003122-A1 | 5HT4-ANTAGONISTIC 4-(AMINOMETHYL)-PIPERIDINE BENZAMIDES | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-01-13 | — | — | WO | disclosed |