Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.45 |
| ▸ | PPARA | Q07869 | 4/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 3/20 | 0.37 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.37 |
| ▸ | FABP3 | P05413 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4728561 | 0.82 | FABP4 (0.46) | PPARGPPARAPPARDPTGS2FABP4 | |
| SCHEMBL4729305 | 0.79 | HPGD (0.42) | PPARGPPARAPPARDPTGS2FABP4 | |
| SCHEMBL4730346 | 0.73 | PSEN1 (0.44) | PPARGPPARAPPARDFABP4FABP5 | |
| SCHEMBL4726682 | 0.70 | AKR1C3 (0.42) | PPARGPPARA | |
| SCHEMBL4727902 | 0.70 | PPARA (0.42) | PPARGPPARAPPARDHPGD | |
| SCHEMBL1715 | 0.64 | LMNA (0.59) | ALDH1A1KMT2AMEN1HTR1AADRA1A | |
| SCHEMBL65737 | 0.64 | LMNA (0.59) | ALDH1A1KMT2AMEN1HTR1AADRA1A | |
| SCHEMBL67237 | 0.64 | LMNA (0.59) | ALDH1A1KMT2AMEN1HTR1AADRA1A | |
| SCHEMBL20769804 | 0.64 | LMNA (0.59) | ALDH1A1KMT2AMEN1HTR1AADRA1A | |
| SCHEMBL29757088 | 0.64 | LMNA (0.59) | ALDH1A1KMT2AMEN1HTR1AADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035359-A2 | OXIMINOPHENOXYALKANOIC ACID AND PHENYLALKANOIC ACID DERIVATIVES | CADILA HEALTHCARE LIMITED (IN) | 2008-03-27 | — | — | WO | claimed |
| WO-2008035359-A2 | OXIMINOPHENOXYALKANOIC ACID AND PHENYLALKANOIC ACID DERIVATIVES | CADILA HEALTHCARE LIMITED (IN) | 2008-03-27 | — | — | WO | disclosed |