Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | LMNA | P02545 | 5/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | PGR | P06401 | 2/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | PDE4A | P27815 | 1/20 | 0.54 |
| ▸ | HRH1 | P35367 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4730662 | 0.86 | ALDH1A1 (0.48) | ALDH1A1LMNAMAPK1HPGDCYP1A2 | |
| SCHEMBL30431499 | 0.84 | ALDH1A1 (0.42) | ALDH1A1LMNAMAPK1HPGDCYP3A4 | |
| SCHEMBL30405946 | 0.83 | ALDH1A1 (0.51) | ALDH1A1LMNAMAPK1HTTCYP3A4 | |
| Bicarbonate SCHEMBL6765194 | 0.83 | ALDH1A1 (0.41) | ALDH1A1LMNAMAPK1HPGDCYP3A4 | |
| Benzophenone SCHEMBL27596948 | 0.83 | ALDH1A1 (0.41) | ALDH1A1LMNAMAPK1HPGDCYP3A4 | |
| SCHEMBL63069 | 0.81 | TAS1R3 (0.42) | ALDH1A1LMNAMAPK1CYP3A4CA2 | |
| SCHEMBL10293784 | 0.80 | LMNA (0.68) | ALDH1A1LMNAMAPK1HPGDCYP1A2 | |
| SCHEMBL4285794 | 0.80 | MAPK1 (0.57) | ALDH1A1LMNAMAPK1HPGDCYP1A2 | |
| Octisalate SCHEMBL2783632 | 0.77 | LMNA (0.69) | ALDH1A1LMNAMAPK1HPGDCYP1A2 | |
| Octisalate SCHEMBL5457329 | 0.77 | LMNA (0.69) | ALDH1A1LMNAMAPK1HPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080095720-A1 | Vitamin A, Vitamin B3, humectant, aloe vera, pigmentary or sunscreen grade metal oxide, Vitamin C, resorcinol, an antisebum agent, or a hydroxy fatty acid and capsazepine; wrinkle resistance cosmetics | CONOPCO, INC., D/B/A UNILEVER (US) | 2008-04-24 | — | — | US | disclosed |
| WO-2008046788-A1 | SKIN BENEFIT COMPOSITIONS WITH A VANILLOID RECEPTOR ANTAGONIST | UNILEVER PLC (GB) | 2008-04-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080095720-A1 | Vitamin A, Vitamin B3, humectant, aloe vera, pigmentary or sunscreen grade metal oxide, Vitamin C, resorcinol, an antisebum agent, or a hydroxy fatty acid and capsazepine; wrinkle resistance cosmetics | RBP4, ALOX15, ALOX15B | ALDH1A1 719/4885LMNA 1678/4885MAPK1 3349/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.