Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4730301 | 0.84 | MAPT (0.40) | ALDH1A1MAPTL3MBTL1KMT2AHSD17B10 | |
| SCHEMBL4733534 | 0.84 | AKR1C3 (0.35) | ALDH1A1MAPTL3MBTL1KMT2AHSD17B10 | |
| SCHEMBL1019446 | 0.82 | POLB (0.38) | ALDH1A1MAPTL3MBTL1KMT2AHSD17B10 | |
| SCHEMBL1018834 | 0.81 | CHRM3 (0.44) | ALDH1A1MAPTKMT2AMEN1TP53 | |
| SCHEMBL4733183 | 0.81 | SMN1; SMN2 (0.36) | MAPTL3MBTL1KMT2AHSD17B10MEN1 | |
| SCHEMBL4733778 | 0.80 | ALDH1A1 (0.38) | ALDH1A1L3MBTL1KMT2AMEN1KDM4E | |
| SCHEMBL4733467 | 0.79 | CA2 (0.44) | MAPTKMT2AMEN1KDM4EPOLB | |
| SCHEMBL1024112 | 0.79 | CHRM3 (0.40) | MAPTKMT2AMEN1KDM4ENPSR1 | |
| SCHEMBL4729048 | 0.78 | RXFP1 (0.35) | ALDH1A1L3MBTL1KMT2AMEN1LMNA | |
| SCHEMBL4731393 | 0.76 | CA2 (0.39) | KMT2AMEN1POLBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008053044-A2 | HETARYL CARBON ACID-N-(BIPHEN-2-YL)AMIDE COMPOUNDS | BASF SE (DE) | 2008-05-08 | — | — | WO | claimed |
| WO-2008053044-A2 | HETARYL CARBON ACID-N-(BIPHEN-2-YL)AMIDE COMPOUNDS | BASF SE (DE) | 2008-05-08 | — | — | WO | disclosed |