Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 11/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4733467 | 0.91 | CA2 (0.44) | PTGS2PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL1019446 | 0.87 | POLB (0.38) | ALDH1A1MEN1KMT2AL3MBTL1PTGDR2 | |
| SCHEMBL1018834 | 0.85 | CHRM3 (0.44) | ALDH1A1GAAJAK2JAK3NPC1 | |
| SCHEMBL4731393 | 0.84 | CA2 (0.39) | PTGS2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL4733183 | 0.83 | SMN1; SMN2 (0.36) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL1024112 | 0.81 | CHRM3 (0.40) | NPC1RAB9AKDM4EMEN1KMT2A | |
| SCHEMBL4733534 | 0.80 | AKR1C3 (0.35) | ALDH1A1KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL4732011 | 0.80 | ALDH1A1 (0.37) | ALDH1A1NPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL4729048 | 0.78 | RXFP1 (0.35) | ALDH1A1MEN1KMT2ARXFP1L3MBTL1 | |
| SCHEMBL6255403 | 0.78 | MAPT (0.33) | ALDH1A1RAB9AKDM4ESMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008053044-A2 | HETARYL CARBON ACID-N-(BIPHEN-2-YL)AMIDE COMPOUNDS | BASF SE (DE) | 2008-05-08 | — | — | WO | disclosed |