Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.44 |
| ▸ | CA9 | Q16790 | 5/20 | 0.44 |
| ▸ | CA12 | O43570 | 4/20 | 0.44 |
| ▸ | CA1 | P00915 | 4/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 9/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 8/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | POLQ | O75417 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4733778 | 0.91 | ALDH1A1 (0.38) | PTGS2PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL4731393 | 0.91 | CA2 (0.39) | CA2CA9CA12CA1PTGS2 | |
| SCHEMBL1019446 | 0.86 | POLB (0.38) | MEN1POLBKMT2AMAPT | |
| SCHEMBL4732975 | 0.85 | CA12 (0.44) | CA2CA9CA12CA1PTGS2 | |
| SCHEMBL1018834 | 0.84 | CHRM3 (0.44) | MEN1KMT2AMAPT | |
| SCHEMBL4733183 | 0.82 | SMN1; SMN2 (0.36) | MEN1POLBKMT2AMAPT | |
| SCHEMBL1024112 | 0.80 | CHRM3 (0.40) | MEN1KMT2AKDM4EMAPT | |
| SCHEMBL4733534 | 0.79 | AKR1C3 (0.35) | MEN1POLBKMT2AKDM4EMAPT | |
| SCHEMBL4732011 | 0.79 | ALDH1A1 (0.37) | MEN1POLBKMT2AKDM4EMAPT | |
| SCHEMBL4729048 | 0.77 | RXFP1 (0.35) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008053044-A2 | HETARYL CARBON ACID-N-(BIPHEN-2-YL)AMIDE COMPOUNDS | BASF SE (DE) | 2008-05-08 | — | — | WO | claimed |
| WO-2008053044-A2 | HETARYL CARBON ACID-N-(BIPHEN-2-YL)AMIDE COMPOUNDS | BASF SE (DE) | 2008-05-08 | — | — | WO | disclosed |