Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4730924 | 0.83 | ALDH1A1 (0.32) | ALDH1A1CYP3A4MAPK1TDP1 | |
| SCHEMBL4730936 | 0.82 | LMNA (0.32) | ALDH1A1CYP3A4MAPK1TDP1 | |
| SCHEMBL4735468 | 0.81 | LMNA (0.32) | ALDH1A1CYP3A4MAPK1TDP1 | |
| SCHEMBL4785987 | 0.76 | PARG (0.38) | TDP1MEN1KMT2A | |
| SCHEMBL21390569 | 0.75 | KMT2A (0.48) | MEN1KMT2ANOX1 | |
| SCHEMBL30193036 | 0.75 | KMT2A (0.48) | MEN1KMT2ANOX1 | |
| SCHEMBL4736205 | 0.75 | HTT (0.35) | MEN1KMT2A | |
| SCHEMBL4733960 | 0.75 | PIK3CD (0.36) | MEN1KMT2A | |
| SCHEMBL19319666 | 0.73 | KDM4E (0.37) | ALDH1A1CYP3A4MAPK1TDP1MEN1 | |
| SCHEMBL4734675 | 0.73 | KDM4E (0.37) | ALDH1A1CYP3A4MAPK1TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008061029-A1 | ARYL SULFONAMIDE DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |