Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 8/20 | 0.35 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.34 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | KDM4A | O75164 | 5/20 | 0.30 |
| ▸ | KDM4C | Q9H3R0 | 5/20 | 0.30 |
| ▸ | KDM5A | P29375 | 1/20 | 0.30 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.30 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.30 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11586917 | 0.82 | KDM4E (0.34) | TERTPAOXDNM1TGFBR1KDM4E | |
| SCHEMBL9245470 | 0.77 | TERT (0.33) | TERTDNM1SIRT1 | |
| SCHEMBL194934 | 0.77 | HDAC3 (0.46) | TGFBR1KDM4E | |
| SCHEMBL4732318 | 0.77 | TGFBR1 (0.39) | TGFBR1KDM4E | |
| SCHEMBL7062743 | 0.75 | TDP1 (0.34) | — | |
| SCHEMBL195107 | 0.73 | ALDH1A1 (0.47) | KDM4E | |
| SCHEMBL19579925 | 0.73 | TDP1 (0.39) | TGFBR1 | |
| SCHEMBL28992627 | 0.73 | DNM1 (0.39) | PAOXDNM1KDM4E | |
| SCHEMBL7521579 | 0.72 | CRBN (0.39) | TERTPAOXDNM1SIRT1KDM4A | |
| SCHEMBL2926477 | 0.72 | HSP90AA1 (0.50) | DNM1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9339549-B2 | Cationic graft-copolymer for drug delivery system | ONISHI YASUHIKO (JP) | 2016-05-17 | — | — | US | disclosed |
| EP-1583782-B1 | CATIONIC GRAFT-COPOLYMER FOR NON-VIRAL GENE DELIVERY VECTOR | ONISHI YASUHIKO (JP) | 2015-05-06 | — | — | EP | disclosed |
| US-20150072938-A1 | CATIONIC GRAFT-COPOLYMER FOR DRUG DELIVERY SYSTEM | ONISHI YASUHIKO (JP) | 2015-03-12 | — | — | US | disclosed |
| US-20090215167-A1 | Cationic graft-copolymer for non-viral gene delivery vector | ONISHI YASUHIKO | 2009-08-27 | — | — | US | disclosed |
| US-7473733-B2 | Cationic graft-copolymer for non-viral gene delivery vector | ONISHI YASUHIKO | 2009-01-06 | — | — | US | disclosed |
| US-20050287110-A1 | Cationic graft-compolymer for non-viral gene delivery vector | ONISHI YASUHIKO | 2005-12-29 | — | — | US | disclosed |
| US-4816540-A | Cationic graft-copolymer | ONISHI YASUHIKO (JP) | 1989-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150072938-A1 | CATIONIC GRAFT-COPOLYMER FOR DRUG DELIVERY SYSTEM | OGFR, OXGR1, OGFRL1 | TERT 4641/4885PAOX 921/4885DNM1 2350/4885 |
| US-20050287110-A1 | Cationic graft-compolymer for non-viral gene delivery vector | NONO, OGFR, OGFOD1 | TERT 3674/4885PAOX 202/4885DNM1 3562/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.