Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 3/20 | 0.44 |
| ▸ | PRKAA2 | P54646 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4737659 | 0.92 | KDM4E (0.47) | OPRM1OPRK1ALDH1A1KDM4ETSHR | |
| SCHEMBL4738909 | 0.90 | TSHR (0.44) | OPRM1OPRK1ALDH1A1KDM4ETSHR | |
| SCHEMBL4735555 | 0.90 | TSHR (0.53) | OPRM1OPRK1ALDH1A1KDM4ETSHR | |
| SCHEMBL4737305 | 0.89 | DRD4 (0.45) | ALDH1A1KDM4ETSHRACHEDRD2 | |
| SCHEMBL4733795 | 0.88 | KDM4E (0.51) | OPRM1OPRK1ALDH1A1KDM4ETSHR | |
| SCHEMBL4738924 | 0.87 | OPRM1 (0.40) | OPRM1OPRK1ALDH1A1KDM4ETSHR | |
| SCHEMBL4735549 | 0.86 | MEN1 (0.43) | OPRM1OPRK1ALDH1A1KDM4ETSHR | |
| SCHEMBL4735426 | 0.86 | OPRM1 (0.43) | OPRM1OPRK1ALDH1A1KDM4ETSHR | |
| SCHEMBL4736796 | 0.85 | OPRM1 (0.49) | OPRM1OPRK1ALDH1A1KDM4ETSHR | |
| SCHEMBL4737014 | 0.85 | HDAC2 (0.42) | OPRM1OPRK1ALDH1A1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |