Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.35 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4736765 | 0.81 | CYP19A1 (0.43) | CYP19A1CNR2HPGDSMN1; SMN2KLKB1 | |
| SCHEMBL8193347 | 0.80 | ALDH1A1 (0.47) | ALDH1A1LMNACYP19A1HSP90AB1CNR2 | |
| SCHEMBL8191026 | 0.78 | ALDH1A1 (0.43) | ALDH1A1LMNACYP19A1HSP90AB1CNR2 | |
| SCHEMBL4735258 | 0.77 | ALDH1A1 (0.52) | ALDH1A1LMNACNR2SMN1; SMN2 | |
| SCHEMBL8185813 | 0.77 | CNR2 (0.48) | ALDH1A1LMNACYP19A1HSP90AB1CNR2 | |
| SCHEMBL4739106 | 0.76 | NPC1 (0.41) | CNR2SMN1; SMN2CNR1 | |
| SCHEMBL8189301 | 0.76 | GRIA2 (0.41) | LMNACNR2KLKB1CNR1 | |
| SCHEMBL8190064 | 0.76 | CYP3A4 (0.42) | LMNACNR2CNR1 | |
| SCHEMBL4733577 | 0.76 | TLR7 (0.40) | ALDH1A1LMNACNR2SMN1; SMN2CNR1 | |
| SCHEMBL8184199 | 0.74 | MAPK14 (0.44) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |