Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.43 |
| ▸ | CNR2 | P34972 | 3/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4733672 | 0.81 | ALDH1A1 (0.44) | CYP19A1CNR2KLKB1CNR1HPGD | |
| SCHEMBL4738910 | 0.78 | CACNA1H (0.42) | CYP19A1CNR2KLKB1CNR1MAPT | |
| SCHEMBL8190064 | 0.77 | CYP3A4 (0.42) | CNR2CNR1MAPTTP53 | |
| SCHEMBL4735258 | 0.77 | ALDH1A1 (0.52) | CNR2MAPTHTTTP53SMN1; SMN2 | |
| SCHEMBL8184199 | 0.74 | MAPK14 (0.44) | CNR2CNR1MAPTTP53 | |
| SCHEMBL4739106 | 0.74 | NPC1 (0.41) | CNR2CNR1MAPTSMN1; SMN2 | |
| SCHEMBL4733577 | 0.73 | TLR7 (0.40) | CNR2CNR1MAPTTP53SMN1; SMN2 | |
| SCHEMBL3818747 | 0.73 | CNR2 (0.47) | CNR2CNR1MAPTHTTTP53 | |
| SCHEMBL4734930 | 0.72 | ALDH1A1 (0.45) | CNR2CNR1MAPTHPGDCYP1A2 | |
| SCHEMBL4738668 | 0.72 | CNR2 (0.40) | CNR2CNR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |