Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | KDM5A | P29375 | 3/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | GRN | P28799 | 1/20 | 0.32 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.32 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.32 |
| ▸ | RBP4 | P02753 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4735033 | 0.92 | PLA2G4A (0.36) | PLA2G4AKDM4EKDM5AKDM5BKDM4A | |
| SCHEMBL4733881 | 0.80 | GABRG2 (0.35) | SMYD3 | |
| SCHEMBL151394 | 0.79 | SMYD3 (0.50) | PLA2G4AKDM4EKDM5AKDM5BSMYD3 | |
| SCHEMBL3689829 | 0.77 | PLA2G4A (0.40) | PLA2G4AKDM4EKDM5AKDM5BKDM4C | |
| SCHEMBL710279 | 0.76 | KDM5A (0.54) | PLA2G4AKDM4EKDM5AKDM5BKDM4C | |
| SCHEMBL4735031 | 0.76 | SCD (0.32) | CNR2 | |
| SCHEMBL4901656 | 0.76 | PLA2G4A (0.39) | PLA2G4AKDM4EKDM5AKDM5BKDM4C | |
| SCHEMBL3690823 | 0.76 | PLA2G4A (0.39) | PLA2G4AKDM4EKDM5AKDM5BKDM4A | |
| SCHEMBL4590582 | 0.76 | PLA2G4A (0.42) | PLA2G4AKDM4EKDM5AKDM5BKDM4A | |
| SCHEMBL25235849 | 0.75 | CPB2 (0.47) | PLA2G4AKDM4EKDM5AKDM5BSMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | disclosed |
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | disclosed |