Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CLK1 | P49759 | 4/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 4/20 | 0.42 |
| ▸ | CLK2 | P49760 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3819010 | 0.76 | RNF4 (0.47) | KMT2AMEN1DRD2DRD3CHRM2 | |
| SCHEMBL4736992 | 0.76 | MEN1 (0.43) | KMT2AMEN1DRD2DRD3PDK1 | |
| SCHEMBL3824522 | 0.74 | CHRM1 (0.47) | KMT2AMEN1DRD2DRD3CHRM2 | |
| SCHEMBL3819221 | 0.74 | CHRM2 (0.44) | KMT2AMEN1DRD2DRD3CHRM2 | |
| SCHEMBL4737523 | 0.73 | ALDH1A1 (0.45) | KMT2AMEN1CHRM2CHRM1CHRM3 | |
| SCHEMBL4735333 | 0.72 | ALDH1A1 (0.48) | KMT2AMEN1DRD2DRD3CHRM2 | |
| SCHEMBL4737670 | 0.71 | SMN1; SMN2 (0.46) | KMT2AMEN1DRD2DRD3PDK1 | |
| SCHEMBL3053871 | 0.71 | CNR2 (0.41) | DRD2DRD3CHRM2CHRM1CHRM3 | |
| SCHEMBL27594337 | 0.70 | CNR1 (0.41) | DRD2DRD3ALDH1A1 | |
| SCHEMBL3819014 | 0.69 | CNR2 (0.46) | DRD2DRD3ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |