Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | DRD3 | P35462 | 3/20 | 0.38 |
| ▸ | TSPO | P30536 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | BCL2A1 | Q16548 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4734077 | 0.92 | TP53 (0.40) | MEN1KMT2AMAPTGAASMN1; SMN2 | |
| SCHEMBL3819010 | 0.78 | RNF4 (0.47) | MEN1KMT2ADRD2DRD3TSPO | |
| SCHEMBL4734150 | 0.76 | KMT2A (0.48) | MEN1KMT2AALDH1A1LMNADRD2 | |
| SCHEMBL4737523 | 0.76 | ALDH1A1 (0.45) | MEN1KMT2AMAPTGAASMN1; SMN2 | |
| SCHEMBL3819221 | 0.75 | CHRM2 (0.44) | MEN1KMT2ADRD2DRD3TSPO | |
| SCHEMBL4735333 | 0.74 | ALDH1A1 (0.48) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL4737670 | 0.73 | SMN1; SMN2 (0.46) | MEN1KMT2AMAPTGAASMN1; SMN2 | |
| SCHEMBL3053871 | 0.72 | CNR2 (0.41) | DRD2DRD3TSPOBCL2A1CHRM2 | |
| SCHEMBL27594337 | 0.71 | CNR1 (0.41) | MAPTGAASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL3824522 | 0.71 | CHRM1 (0.47) | MEN1KMT2AALDH1A1LMNADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |