Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1L | O00429 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4737991 | 0.89 | KDM4E (0.43) | KDM4ELMNAALDH1A1L3MBTL1CYP1A2 | |
| SCHEMBL3060142 | 0.86 | ALDH1A1 (0.52) | DNM1LKDM4EALDH1A1RAB9ANPC1 | |
| SCHEMBL3816465 | 0.84 | MAPK14 (0.43) | KDM4ELMNAALDH1A1L3MBTL1CYP1A2 | |
| SCHEMBL4734821 | 0.79 | RAB9A (0.43) | DNM1LKDM4EALDH1A1L3MBTL1CYP3A4 | |
| SCHEMBL4735282 | 0.78 | BCHE (0.46) | LMNAL3MBTL1HPGDHSD17B10BCHE | |
| Hydrochloric Acid SCHEMBL4739571 | 0.77 | BCHE (0.45) | LMNAL3MBTL1HPGDHSD17B10BCHE | |
| SCHEMBL3063987 | 0.74 | GRIN1 (0.43) | LMNAGRM1 | |
| SCHEMBL3824769 | 0.73 | CFTR (0.55) | DNM1LLMNAALDH1A1BCHEGRM1 | |
| SCHEMBL3069103 | 0.72 | L3MBTL1 (0.52) | LMNAL3MBTL1CYP3A4SMN1; SMN2MAPK14 | |
| SCHEMBL3816827 | 0.72 | LMNA (0.63) | KDM4ELMNAALDH1A1L3MBTL1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |