Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 5/20 | 0.40 |
| ▸ | DRD4 | P21917 | 3/20 | 0.40 |
| ▸ | DRD3 | P35462 | 3/20 | 0.40 |
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | HTR7 | P34969 | 3/20 | 0.40 |
| ▸ | HTR1A | P08908 | 3/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | SLC27A1 | Q6PCB7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3830332 | 0.84 | MEN1 (0.45) | ALDH1A1TSHRRAB9AGAAMAPT | |
| SCHEMBL3823632 | 0.82 | L3MBTL1 (0.45) | ALDH1A1TSHRRAB9ADRD2DRD4 | |
| SCHEMBL3860025 | 0.81 | L3MBTL1 (0.53) | ALDH1A1TSHRRAB9ADRD2DRD4 | |
| SCHEMBL3827091 | 0.81 | L3MBTL1 (0.44) | ALDH1A1TSHRHDAC10KDM4ECHRM5 | |
| SCHEMBL4735130 | 0.81 | KMT2A (0.45) | ALDH1A1TSHRNPC1RAB9AGAA | |
| SCHEMBL4737954 | 0.81 | KDM4E (0.45) | ALDH1A1TSHRCYP3A4DRD2DRD4 | |
| SCHEMBL3830922 | 0.80 | L3MBTL1 (0.43) | ALDH1A1TSHRHSD17B10CYP3A4DRD2 | |
| SCHEMBL4735586 | 0.79 | LMNA (0.53) | ALDH1A1TSHRGAAMAPTCYP3A4 | |
| SCHEMBL4737551 | 0.79 | ALDH1A1 (0.44) | ALDH1A1RAD52NPC1RAB9AGAA | |
| SCHEMBL4735615 | 0.79 | MAPK14 (0.45) | ALDH1A1TSHRRAB9ADRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |