Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 3/20 | 0.38 |
| ▸ | MLNR | O43193 | 1/20 | 0.38 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.36 |
| ▸ | ME2 | P23368 | 1/20 | 0.36 |
| ▸ | ME1 | P48163 | 1/20 | 0.36 |
| ▸ | ME3 | Q16798 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4735235 | 0.89 | GAA (0.47) | MAPK14MLNRKDM4EOPRM1MAPK8 | |
| SCHEMBL4737014 | 0.88 | HDAC2 (0.42) | MAPK14MLNRKDM4EOPRM1OPRK1 | |
| SCHEMBL4735426 | 0.88 | OPRM1 (0.43) | MAPK14HSD17B10KDM4EOPRM1OPRK1 | |
| SCHEMBL4738924 | 0.86 | OPRM1 (0.40) | MAPK14KDM4EOPRM1OPRK1CXCR2 | |
| SCHEMBL4733795 | 0.85 | KDM4E (0.51) | MAPK14KDM4EOPRM1OPRK1CXCR2 | |
| SCHEMBL4737305 | 0.85 | DRD4 (0.45) | MAPK14KDM4ECXCR2ACHEALDH1A1 | |
| SCHEMBL4735512 | 0.85 | HRH3 (0.43) | MAPK14HSD17B10OPRM1OPRK1ME2 | |
| SCHEMBL4738909 | 0.85 | TSHR (0.44) | MAPK14KDM4EOPRM1OPRK1CXCR2 | |
| SCHEMBL3054819 | 0.84 | ACHE (0.45) | MLNRPRKAA2KDM4EOPRM1OPRK1 | |
| SCHEMBL4738700 | 0.84 | MAPK14 (0.39) | MAPK14MLNRHSD17B10KDM4ECXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |