Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4740422 | 0.87 | POLB (0.50) | USP2GAALMNASMN1; SMN2CYP2C19 | |
| SCHEMBL4740078 | 0.86 | GAA (0.50) | DPP4USP2GAALMNASMN1; SMN2 | |
| SCHEMBL4736709 | 0.84 | LMNA (0.57) | DPP4LMNASMN1; SMN2CYP2C19ALDH1A1 | |
| SCHEMBL4737593 | 0.84 | LMNA (0.57) | DPP4LMNASMN1; SMN2CYP2C19ALDH1A1 | |
| SCHEMBL4736650 | 0.84 | P2RX7 (0.53) | USP2GAALMNASMN1; SMN2CYP2C19 | |
| SCHEMBL4740625 | 0.83 | LMNA (0.57) | LMNASMN1; SMN2CYP2C19ALDH1A1L3MBTL1 | |
| SCHEMBL4740908 | 0.83 | P2RX7 (0.49) | USP2GAALMNACYP2C19HSD17B10 | |
| SCHEMBL4737612 | 0.83 | LMNA (0.50) | DPP4USP2GAALMNASMN1; SMN2 | |
| SCHEMBL4738276 | 0.82 | CYP2C19 (0.52) | DPP4GAALMNASMN1; SMN2CYP2C19 | |
| SCHEMBL4738286 | 0.81 | LMNA (0.55) | DPP4GAALMNASMN1; SMN2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008087654-A2 | PIPERIDINES AS INHIBITORS OF 11β-HYDROXYSTEROID DEHYDROGENASE TYPE 1 | CADILA HEALTHCARE LIMITED (IN) | 2008-07-24 | — | — | WO | claimed |