Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 2/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.43 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | MTOR | P42345 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4786637 | 0.93 | SLC6A4 (0.48) | PDE2AAKR1C3AKR1C2SLC6A9LMNA | |
| SCHEMBL4739538 | 0.85 | SLC6A9 (0.52) | SLC6A9LMNAMEN1KMT2ANPC1 | |
| SCHEMBL4739366 | 0.84 | SLC6A9 (0.53) | SLC6A9LMNAMEN1KMT2ANPC1 | |
| SCHEMBL3981 | 0.80 | HTR1A (0.46) | SLC6A9LMNAMEN1KMT2ANPC1 | |
| Oxalic Acid SCHEMBL4736671 | 0.78 | SLC6A4 (0.63) | SLC6A9LMNAMEN1KMT2ANPC1 | |
| SCHEMBL3555 | 0.78 | OPRM1 (0.43) | SLC6A9LMNAMEN1KMT2ANPC1 | |
| SCHEMBL10359727 | 0.77 | SLC7A5 (0.52) | SLC6A9LMNAMEN1KMT2ANPC1 | |
| Oxalic Acid SCHEMBL4786635 | 0.74 | SLC6A4 (0.57) | SLC6A9LMNAMEN1KMT2ANPC1 | |
| SCHEMBL4740057 | 0.71 | SLC6A9 (0.48) | AKR1C3AKR1C2SLC6A9SLC6A4CYP1A2 | |
| SCHEMBL3501 | 0.70 | SMN1; SMN2 (0.40) | NPC1RAB9ASMN1; SMN2HPGDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008081477-A1 | 3-ARYLOXY 3-SUBSTITUTED PROPANAMINES | NATCO PHARMA LIMITED (IN) | 2008-07-10 | — | — | WO | disclosed |