Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 6/20 | 0.53 |
| ▸ | UTS2R | Q9UKP6 | 4/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | MTOR | P42345 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.45 |
| ▸ | CNR1 | P21554 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4739538 | 0.90 | SLC6A9 (0.52) | SLC6A9MEN1KMT2ALMNANPC1 | |
| SCHEMBL4736674 | 0.84 | PDE2A (0.43) | SLC6A9PPARAMEN1KMT2ALMNA | |
| SCHEMBL3981 | 0.83 | HTR1A (0.46) | SLC6A9MEN1KMT2ALMNANPC1 | |
| SCHEMBL3555 | 0.80 | OPRM1 (0.43) | SLC6A9PPARGPPARAMEN1KMT2A | |
| SCHEMBL10359727 | 0.79 | SLC7A5 (0.52) | SLC6A9PPARGPPARAMEN1KMT2A | |
| SCHEMBL4786637 | 0.78 | SLC6A4 (0.48) | SLC6A9MEN1KMT2ALMNANPC1 | |
| Oxalic Acid SCHEMBL4739361 | 0.76 | SLC6A4 (0.70) | SLC6A9PPARGPPARAMEN1KMT2A | |
| SCHEMBL3800 | 0.76 | CACNA2D1 (0.39) | PPARGPPARALMNASLC6A2SLC6A4 | |
| SCHEMBL4785574 | 0.75 | SLC6A4 (0.76) | SLC6A9MEN1KMT2ALMNANPC1 | |
| SCHEMBL16347642 | 0.74 | SLC6A9 (0.47) | SLC6A9PPARGPPARAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008081477-A1 | 3-ARYLOXY 3-SUBSTITUTED PROPANAMINES | NATCO PHARMA LIMITED (IN) | 2008-07-10 | — | — | WO | disclosed |