Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 3/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 9/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.37 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.37 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.36 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4733659 | 0.83 | CACNA1H (0.41) | MAPK14PDK1PDK2PDK3PDK4 | |
| SCHEMBL4735834 | 0.81 | MAPK14 (0.46) | MAPK14PDK1LMNAPDK2PDK3 | |
| SCHEMBL4737955 | 0.81 | OPRM1 (0.43) | MAPK14PDK1 | |
| SCHEMBL4734783 | 0.80 | OPRM1 (0.40) | MAPK14LMNA | |
| SCHEMBL4786222 | 0.78 | KDM4E (0.49) | MAPK14 | |
| SCHEMBL4734903 | 0.78 | KDM4E (0.41) | MAPK14LMNA | |
| SCHEMBL4733765 | 0.78 | CNR2 (0.36) | MAPK14PDK1PDK2PDK3PDK4 | |
| SCHEMBL4734158 | 0.78 | DRD4 (0.43) | MAPK14LMNA | |
| SCHEMBL4736796 | 0.76 | OPRM1 (0.49) | — | |
| SCHEMBL4738192 | 0.75 | HRH3 (0.42) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |