Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4739554 | 0.81 | RAB9A (0.56) | RAB9AMAPTALDH1A1KDM4EMCL1 | |
| SCHEMBL3069128 | 0.77 | RAB9A (0.71) | RAB9AMAPTALDH1A1KDM4EMCL1 | |
| SCHEMBL15996870 | 0.76 | NPC1 (0.58) | RAB9AMAPTALDH1A1KDM4EMCL1 | |
| SCHEMBL5737663 | 0.75 | TSHR (0.55) | RAB9AMAPTALDH1A1KDM4EMCL1 | |
| SCHEMBL10943491 | 0.75 | HPGD (0.78) | RAB9AMAPTALDH1A1KDM4ETSHR | |
| SCHEMBL4737730 | 0.74 | KMT2A (0.60) | RAB9AMAPTALDH1A1KDM4ETSHR | |
| SCHEMBL6082056 | 0.73 | TSHR (0.56) | RAB9AMAPTALDH1A1KDM4EMCL1 | |
| SCHEMBL21382113 | 0.73 | ALDH1A1 (0.47) | RAB9AMAPTALDH1A1KDM4EMCL1 | |
| SCHEMBL1690744 | 0.73 | FAAH (0.69) | RAB9AMAPTALDH1A1KDM4EMCL1 | |
| SCHEMBL9711966 | 0.73 | MAPT (0.62) | RAB9AMAPTALDH1A1KDM4EMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008086462-A2 | AMINO-SUBSTITUTED QUINAZOLINE DERIVATIVES AS INHIBITORS OF β-CANTENIN/TCF-4 PATHWAY AND CANCER TREATMENT AGENTS | WYETH (US) | 2008-07-17 | — | — | WO | disclosed |