Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DBH | P09172 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4736170 | 0.85 | KMT2A (0.58) | DBHKMT2ARXFP1KDM4EMEN1 | |
| SCHEMBL4739836 | 0.85 | KMT2A (0.49) | DBHKMT2ARXFP1KDM4EMEN1 | |
| SCHEMBL4737872 | 0.76 | KMT2A (0.51) | DBHKMT2ARXFP1KDM4EMEN1 | |
| SCHEMBL4738142 | 0.73 | CYP11B1 (0.50) | KMT2ARXFP1KDM4EMEN1RECQL | |
| SCHEMBL4738830 | 0.73 | KMT2A (0.61) | KMT2ARXFP1KDM4EMEN1RECQL | |
| SCHEMBL4739765 | 0.70 | RAB9A (0.46) | KMT2ARXFP1KDM4EMEN1RECQL | |
| SCHEMBL4738141 | 0.70 | RAB9A (0.46) | DBHKMT2ARXFP1KDM4EMEN1 | |
| SCHEMBL4798687 | 0.70 | BCL2L1 (0.46) | DBHKMT2ARXFP1KDM4EMEN1 | |
| SCHEMBL9372580 | 0.69 | RAB9A (0.50) | KMT2ARXFP1KDM4EMEN1RECQL | |
| SCHEMBL4739723 | 0.69 | RAB9A (0.45) | KMT2ARXFP1KDM4EMEN1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008085008-A1 | T-CELL INHIBITING COMPOUNDS AND THEIR USE FOR THE TREATMENT OF T-CELL-MEDIATED DISEASES | MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE (KR) | 2008-07-17 | — | — | WO | disclosed |