SCHEMBL4738387

SCHEMBL4738387

ClSc1nc2ccccc2s1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.70
HSD17B10 Q99714 5/20 0.70
HPGD P15428 5/20 0.70
FBP1 P09467 3/20 0.70
ALOX15 P16050 3/20 0.70
TDP1 Q9NUW8 2/20 0.70
ADRA2A P08913 1/20 0.70
ADORA3 P0DMS8 1/20 0.70
DRD2 P14416 1/20 0.70
ADRA2B P18089 1/20 0.70
ADRA2C P18825 1/20 0.70
DRD1 P21728 1/20 0.70
MC5R P33032 1/20 0.70
OPRM1 P35372 1/20 0.70
DRD3 P35462 1/20 0.70
OPRK1 P41145 1/20 0.70
CCR2 P41597 1/20 0.70
HTR6 P50406 1/20 0.70
SLC6A3 Q01959 1/20 0.70
PDK1 Q15118 1/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzothiazyl Disulfide SCHEMBL29356396 0.83 ALDH1A1 (1.00) ALDH1A1HSD17B10HPGDFBP1ALOX15
Benzothiazyl Disulfide SCHEMBL11095350 0.83 ALDH1A1 (1.00) ALDH1A1HSD17B10HPGDFBP1ALOX15
SCHEMBL30005981 0.83 ALDH1A1 (0.76) ALDH1A1HSD17B10HPGDFBP1ALOX15
Benzothiazyl Disulfide SCHEMBL23527 0.83 ALDH1A1 (1.00) ALDH1A1HSD17B10HPGDFBP1ALOX15
SCHEMBL381557 0.83 ALDH1A1 (0.76) ALDH1A1HSD17B10HPGDFBP1ALOX15
SCHEMBL25340942 0.82 ALDH1A1 (0.68) ALDH1A1HSD17B10HPGDFBP1ALOX15
SCHEMBL29906665 0.82 ALDH1A1 (0.68) ALDH1A1HSD17B10HPGDFBP1ALOX15
SCHEMBL9799786 0.81 ALDH1A1 (0.73) ALDH1A1HSD17B10HPGDFBP1ALOX15
Benzothiazyl Disulfide SCHEMBL3787918 0.81 ALDH1A1 (0.96) ALDH1A1HSD17B10HPGDFBP1ALOX15
Benzothiazyl Disulfide SCHEMBL8609896 0.81 ALDH1A1 (0.96) ALDH1A1HSD17B10HPGDFBP1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024141927-A1 A PROCESS FOR THE PREPARATION OF N, N-DISUBSTITUTED BENZOTHIAZOLE-2-SULFENAMIDES NITREX CHEMICALS INDIA LIMITED (IN) 2024-07-04 WO claimed
US-7291741-B2 Process of production of n-alkyl-2-benzthiazolysulfeneimides, device for their production and method of their purification DUSLO A.S. (SK) 2007-11-06 US claimed
EP-1438301-B1 PROCESS OF PRODUCTION OF N-ALKYL-2-BENZTHIAZOLYLSULFENEIMIDES AND METHOD OF THEIR PURIFICATION DUSLO AS (SK) 2005-09-07 EP claimed
US-20040210062-A1 Process of production of n-alkyl-2-benzthiazolysulfeneimides, device for their production and method of their purification DUSLO, A.S. (SK) 2004-10-21 US claimed
EP-1438301-A1 PROCESS OF PRODUCTION OF N-ALKYL-2-BENZTHIAZOLYLSULFENEIMIDES, DEVICE FOR THEIR PRODUCTION AND METHOD OF THEIR PURIFICATION DUSLO, a.s. (SK) 2004-07-21 EP claimed
WO-2003014096-A1 PROCESS OF PRODUCTION OF N-ALKYL-2-BENZTHIAZOLYLSULFENEIMIDES, DEVICE FOR THEIR PRODUCTION AND METHOD OF THEIR PURIFICATION DUSLO, A.S. (SK) 2003-02-20 WO claimed
WO-2024141927-A1 A PROCESS FOR THE PREPARATION OF N, N-DISUBSTITUTED BENZOTHIAZOLE-2-SULFENAMIDES NITREX CHEMICALS INDIA LIMITED (IN) 2024-07-04 WO disclosed
WO-2008089093-A2 EFFICIENT PROCESSES FOR PREPARING STEROIDS AND VITAMIN D DERIVATIVES WITH THE UNNATURAL CONFIGURATION AT C20 (20 ALPHA-METHYL) FROM PREGNENOLONE QUATRX PHARMACEUTICALS COMPANY (US) 2008-07-24 WO disclosed
US-20080171728-A1 Efficient Process for Preparing Steroids and Vitamin D Derivatives With the Unnatural Configuration at C20 (20 Alpha-Methyl) from Pregnenolone QUATRX PHARMACEUTICALS CO. 2008-07-17 US disclosed
US-7291741-B2 Process of production of n-alkyl-2-benzthiazolysulfeneimides, device for their production and method of their purification DUSLO A.S. (SK) 2007-11-06 US disclosed
US-7291741-B2 Process of production of n-alkyl-2-benzthiazolysulfeneimides, device for their production and method of their purification DUSLO A.S. (SK) 2007-11-06 US disclosed
EP-1438301-B1 PROCESS OF PRODUCTION OF N-ALKYL-2-BENZTHIAZOLYLSULFENEIMIDES AND METHOD OF THEIR PURIFICATION DUSLO AS (SK) 2005-09-07 EP disclosed
EP-1438301-B1 PROCESS OF PRODUCTION OF N-ALKYL-2-BENZTHIAZOLYLSULFENEIMIDES AND METHOD OF THEIR PURIFICATION DUSLO AS (SK) 2005-09-07 EP disclosed
US-4267340-A BACTERICIDES; SYNTHESIS OF PENICILLINS AND CEPHALOSPORINS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1981-05-12 US disclosed
US-4147696-A VULCANIZATION ACCELERATORS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1979-04-03 US disclosed
US-4071527-A Certain benzothiazole compounds FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1978-01-31 US disclosed
US-4036847-A ANTIBACTERIAL FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1977-07-19 US disclosed
US-4009159-A PENICILLINS FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1977-02-22 US disclosed
US-3993646-A Process for the ring expansion of penicillins to cephalosporin compounds FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1976-11-23 US disclosed
US-3979369-A DIENE POLYMER MONSANTO COMPANY (US) 1976-09-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040210062-A1 Process of production of n-alkyl-2-benzthiazolysulfeneimides, device for their production and method of their purification ACR, APEH, INMT ALDH1A1 4102/4885HSD17B10 3450/4885HPGD 4141/4885
US-20080171728-A1 Efficient Process for Preparing Steroids and Vitamin D Derivatives With the Unnatural Configuration at C20 (20 Alpha-Methyl) from Pregnenolone CYP2R1, CYP24A1, VDR ALDH1A1 1232/4885HSD17B10 86/4885HPGD 101/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.