SCHEMBL4738504

SCHEMBL4738504

C=CCSc1nc2cccnc2o1

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.44
PKM P14618 1/20 0.44
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
L3MBTL1 Q9Y468 3/20 0.40
FAAH O00519 1/20 0.38
DAGLA Q9Y4D2 1/20 0.37
SGMS2 Q8NHU3 3/20 0.36
QPCT Q16769 1/20 0.36
DDAH1 O94760 1/20 0.35
ADRA2C P18825 1/20 0.35
NPC1 O15118 1/20 0.35
TP53 P04637 1/20 0.35
HPGD P15428 1/20 0.35
ALOX15 P16050 1/20 0.35
NFKB1 P19838 1/20 0.35
RAB9A P51151 1/20 0.35
NFKB2 Q00653 1/20 0.35
RELA Q04206 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5203873 0.76 DDAH1 (0.59) SMN1; SMN2PKMMEN1KMT2AL3MBTL1
SCHEMBL1056788 0.74 ELANE (0.49) SMN1; SMN2FAAHDAGLASGMS2NPC1
SCHEMBL9207091 0.71 DDAH1 (0.37) SMN1; SMN2MEN1KMT2AL3MBTL1FAAH
SCHEMBL9217607 0.69 ELANE (0.63) SMN1; SMN2MEN1KMT2AL3MBTL1TP53
SCHEMBL4761063 0.68 L3MBTL1 (0.50) SMN1; SMN2PKMMEN1KMT2AL3MBTL1
SCHEMBL9213887 0.66 TMEM97 (0.34) MEN1KMT2AL3MBTL1DDAH1ADRA2C
SCHEMBL13990839 0.65 CYP1A2 (0.49) SMN1; SMN2PKMMEN1KMT2AL3MBTL1
SCHEMBL22242074 0.65 FAAH (0.46) SMN1; SMN2KMT2AFAAHDAGLASGMS2
SCHEMBL1054682 0.65 DDAH1 (0.49) SMN1; SMN2PKMMEN1KMT2AL3MBTL1
SCHEMBL692444 0.65 L3MBTL1 (0.58) MEN1KMT2AL3MBTL1NPC1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080124732-A1 METHOD FOR OPTICAL MEASUREMENT OF MULTI-STRANDED NUCLEIC ACID FUJIFILM CORPORATION 2008-05-29 US disclosed
EP-1889880-A2 Method for optical measurement of multi-stranded nucleic acid FUJIFILM Corporation (JP) 2008-02-20 EP disclosed
EP-1362894-B1 Method for optical measurement of multi-stranded nucleic acid using cyanine dyes FUJIFILM CORP (JP) 2007-12-19 EP disclosed
US-20050112770-A1 Method for optical measurement of multi-stranded nucleic acid FUJI PHOTO FILM CO., LTD. 2005-05-26 US disclosed