Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.49 |
| ▸ | SGMS2 | Q8NHU3 | 6/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SORD | Q00796 | 1/20 | 0.36 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10278989 | 0.75 | ALDH1A1 (0.41) | SGMS2FAAHKDM4EALDH1A1DAGLA | |
| SCHEMBL2667239 | 0.75 | SGMS2 (0.46) | ELANESGMS2FAAHKDM4EALDH1A1 | |
| SCHEMBL30280440 | 0.75 | SGMS2 (0.46) | ELANESGMS2FAAHKDM4EALDH1A1 | |
| SCHEMBL13310865 | 0.75 | SGMS2 (0.51) | SGMS2FAAHKDM4EALDH1A1DAGLA | |
| SCHEMBL4738504 | 0.74 | SMN1; SMN2 (0.44) | SGMS2FAAHDAGLANPC1TP53 | |
| SCHEMBL13052972 | 0.73 | SGMS2 (0.51) | ELANESGMS2FAAHKDM4EALDH1A1 | |
| SCHEMBL13053003 | 0.73 | SGMS2 (0.51) | ELANESGMS2FAAHKDM4EALDH1A1 | |
| SCHEMBL9207091 | 0.72 | DDAH1 (0.37) | SGMS2FAAHKDM4EALDH1A1DAGLA | |
| SCHEMBL303847 | 0.71 | ELANE (0.58) | ELANEALDH1A1NPC1TP53HPGD | |
| SCHEMBL31155591 | 0.71 | ELANE (0.58) | ELANEALDH1A1NPC1TP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160356681-A1 | MODIFIED CARBOCYANINE DYES AND THEIR CONJUGATES | Life Technologies Corporation | 2016-12-08 | — | — | US | disclosed |
| US-9423323-B2 | Modified carbocyanine dyes and their conjugates | Life Technologies Corporation (US) | 2016-08-23 | — | — | US | disclosed |
| US-9423323-B2 | Modified carbocyanine dyes and their conjugates | Life Technologies Corporation (US) | 2016-08-23 | — | — | US | disclosed |
| US-9382425-B2 | Aza-benzazolium containing cyanine dyes | Life Technologies Corporation (US) | 2016-07-05 | — | — | US | disclosed |
| US-20150247785-A1 | MODIFIED CARBOCYANINE DYES AND THEIR CONJUGATES | Life Technologies Corporation | 2015-09-03 | — | — | US | disclosed |
| US-20150218380-A1 | MODIFIED CARBOCYANINE DYES AND THEIR CONJUGATES | Life Technologies Corporation | 2015-08-06 | — | — | US | disclosed |
| US-20150218380-A1 | MODIFIED CARBOCYANINE DYES AND THEIR CONJUGATES | Life Technologies Corporation | 2015-08-06 | — | — | US | disclosed |
| US-9018396-B2 | Modified carbocyanine dyes and their conjugates | Life Technologies Corporation (US) | 2015-04-28 | — | — | US | disclosed |
| US-20150031579-A1 | Aza-Benzazolium Containing Cyanine Dyes | MOLECULAR PROBES, INC. | 2015-01-29 | — | — | US | disclosed |
| US-8883415-B2 | Aza-benzazolium containing cyanine dyes | Life Technologies Corporation (US) | 2014-11-11 | — | — | US | disclosed |
| US-20030119837-A1 | Pharmaceutical composition for the treatment of CNS and other disorders | PFIZER INC. | 2003-06-26 | — | — | US | disclosed |
| US-20030087928-A1 | Novel anilide compounds and drugs containing the same | KOWA COMPANY, LTD., JAPAN | 2003-05-08 | — | — | US | disclosed |
| US-20020099074-A1 | Novel anilide compounds and drugs containing the same | KOWA COMPANY, LTD.,JAPAN | 2002-07-25 | — | — | US | disclosed |
| US-20020086871-A1 | Pharmaceutical composition for the treatment of CNS and other disorders | O'NEILL BRIAN THOMAS (US) | 2002-07-04 | — | — | US | disclosed |
| EP-1219622-A2 | Pharmaceutical compositions for CNS and other disorders | Pfizer Products Inc. (US) | 2002-07-03 | — | — | EP | disclosed |
| US-20020077487-A1 | Modified carbocyanine dyes and their conjugates | MOLECULAR PROBES, INC. | 2002-06-20 | — | — | US | disclosed |
| US-20020064794-A1 | Modified carbocyanine dyes and their conjugates | MOLECULAR PROBES, INC. | 2002-05-30 | — | — | US | disclosed |
| US-6362208-B1 | ANTICHOLESTEROL AGENT | KOWA COMPANY, LTD. (JP) | 2002-03-26 | — | — | US | disclosed |
| WO-2000066664-A1 | AZA-BENZAZOLIUM CONTAINING CYANINE DYES | MOLECULAR PROBES, INC. (US) | 2000-11-09 | — | — | WO | disclosed |
| EP-1020451-A1 | NOVEL ANILIDE COMPOUNDS AND DRUGS CONTAINING THE SAME | Kowa Co., Ltd. (JP) | 2000-07-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020077487-A1 | Modified carbocyanine dyes and their conjugates | IK, CBR3, DRD5 | ELANE 1842/4885SGMS2 4053/4885FAAH 3897/4885 |
| US-20030087928-A1 | Novel anilide compounds and drugs containing the same | ACAT1, ACAT2, LCAT | ELANE 3993/4885SGMS2 833/4885FAAH 514/4885 |
| US-20030119837-A1 | Pharmaceutical composition for the treatment of CNS and other disorders | CHRNA7, CHRNA5, CHRNA10 | ELANE 2459/4885SGMS2 630/4885FAAH 507/4885 |
| US-20160356681-A1 | MODIFIED CARBOCYANINE DYES AND THEIR CONJUGATES | IK, CBR3, DRD5 | ELANE 1842/4885SGMS2 4053/4885FAAH 3897/4885 |
| US-20020099074-A1 | Novel anilide compounds and drugs containing the same | SOAT1, SOAT2, LCAT | ELANE 2569/4885SGMS2 594/4885FAAH 932/4885 |
| US-20150218380-A1 | MODIFIED CARBOCYANINE DYES AND THEIR CONJUGATES | IK, CBR3, DRD5 | ELANE 1842/4885SGMS2 4053/4885FAAH 3897/4885 |
| US-20150247785-A1 | MODIFIED CARBOCYANINE DYES AND THEIR CONJUGATES | IK, CBR3, DRD5 | ELANE 1842/4885SGMS2 4053/4885FAAH 3897/4885 |
| US-20020086871-A1 | Pharmaceutical composition for the treatment of CNS and other disorders | CHRNA7, CHRNA5, CHRNA10 | ELANE 2459/4885SGMS2 630/4885FAAH 507/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.