Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDAH1 | O94760 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9212294 | 0.79 | SHMT2 (0.51) | FAAHTP53 | |
| SCHEMBL1056788 | 0.72 | ELANE (0.49) | FAAHALDH1A1DAGLAKDM4ENPC1 | |
| SCHEMBL9211417 | 0.71 | PDK1 (0.54) | ALDH1A1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4738504 | 0.71 | SMN1; SMN2 (0.44) | DDAH1ADRA2CFAAHDAGLANPC1 | |
| SCHEMBL9213887 | 0.69 | TMEM97 (0.34) | DDAH1ADRA2CALDH1A1HPGDHSD17B10 | |
| SCHEMBL6213545 | 0.69 | SOAT1 (0.75) | — | |
| SCHEMBL9217607 | 0.67 | ELANE (0.63) | ALDH1A1KDM4ETP53HPGDSMN1; SMN2 | |
| SCHEMBL2624379 | 0.66 | ALDH1A1 (0.45) | FAAHALDH1A1DAGLAKDM4ENPC1 | |
| SCHEMBL9215635 | 0.64 | PDK1 (0.41) | ALDH1A1KDM4ENPC1HPGDRAB9A | |
| SCHEMBL21388620 | 0.64 | SGMS2 (0.41) | FAAHALDH1A1DAGLAKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0668864-A1 | SUBSTITUTED BIPHENYLMETHYLIMIDAZOPYRIDINES | MERCK & CO. INC. (US) | 1995-08-30 | — | — | EP | disclosed |
| EP-0668864-A4 | SUBSTITUTED BIPHENYLMETHYLIMIDAZOPYRIDINES. | MERCK & CO INC (US) | 1995-07-10 | — | — | EP | disclosed |
| EP-0405976-B1 | Azole derivatives and antiulcerative composition containing same | MEIJI SEIKA CO (JP) | 1995-04-05 | — | — | EP | disclosed |
| US-5200407-A | Antisecretory agents | MEIJI SEIKA KABURHIKI KAISHA (JP) | 1993-04-06 | — | — | US | disclosed |
| US-5141946-A | Antisecretory agents; acid resistance | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1992-08-25 | — | — | US | disclosed |
| US-5079255-A | Nontoxic, acid stability | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1992-01-07 | — | — | US | disclosed |
| EP-0405976-A1 | Azole derivatives and antiulcerative composition containing same | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1991-01-02 | — | — | EP | disclosed |