Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 5/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | HRH2 | P25021 | 2/20 | 0.41 |
| ▸ | HRH1 | P35367 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5325814 | 0.92 | TMEM97 (0.42) | UTS2RADRA2BSLC6A2HTR2ASLC6A4 | |
| SCHEMBL5164752 | 0.89 | HTR2A (0.47) | ADRA2BSLC6A2HTR2ASLC6A4SLC6A3 | |
| SCHEMBL5321171 | 0.80 | HTT (0.44) | UTS2RSIGMAR1TMEM97CYP2D6CYP2C9 | |
| SCHEMBL5323549 | 0.78 | GAA (0.43) | ADRA2BSLC6A2HTR2ASLC6A4SLC6A3 | |
| SCHEMBL4739377 | 0.77 | AOC3 (0.44) | ADRA2BSLC6A2HTR2ASLC6A4SLC6A3 | |
| SCHEMBL4740861 | 0.77 | TNF (0.50) | L3MBTL1LMNAHTTNPSR1 | |
| SCHEMBL14017766 | 0.76 | ADRA2B (0.50) | ADRA2BSLC6A2HTR2ASLC6A4SLC6A3 | |
| SCHEMBL13452589 | 0.76 | ADRA2B (0.50) | ADRA2BSLC6A2HTR2ASLC6A4SLC6A3 | |
| SCHEMBL5319055 | 0.75 | NPSR1 (0.47) | UTS2RSIGMAR1TMEM97CYP2D6CYP2C9 | |
| SCHEMBL4740860 | 0.75 | ABCB11 (0.47) | TSHRPOLBRXFP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008081477-A1 | 3-ARYLOXY 3-SUBSTITUTED PROPANAMINES | NATCO PHARMA LIMITED (IN) | 2008-07-10 | — | — | WO | disclosed |