Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5325814 | 0.86 | TMEM97 (0.42) | TMEM97SIGMAR1SLC6A2SLC6A4ADRA2B | |
| SCHEMBL5321066 | 0.85 | NPSR1 (0.39) | GAATMEM97SIGMAR1LMNACYP1A2 | |
| SCHEMBL5322144 | 0.81 | LMNA (0.47) | GAATMEM97SIGMAR1LMNACYP1A2 | |
| SCHEMBL5164752 | 0.78 | HTR2A (0.47) | SLC6A2SLC6A4TSHRADRA2BADRA2C | |
| SCHEMBL4739767 | 0.78 | UTS2R (0.42) | TMEM97SIGMAR1LMNACYP1A2CYP3A4 | |
| SCHEMBL5397721 | 0.76 | SLC6A2 (0.40) | SLC6A2SLC6A4OPRM1OPRD1OPRK1 | |
| SCHEMBL11298724 | 0.72 | OPRM1 (0.46) | SLC6A2SLC6A4OPRM1OPRD1OPRL1 | |
| SCHEMBL14017766 | 0.72 | ADRA2B (0.50) | GAANPSR1SLC6A2SLC6A4TSHR | |
| SCHEMBL13452589 | 0.72 | ADRA2B (0.50) | GAANPSR1SLC6A2SLC6A4TSHR | |
| SCHEMBL31419982 | 0.71 | MEN1 (0.58) | GAATMEM97SIGMAR1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007095756-A1 | NOVEL CENTRAL-NERVOUS SYSTEM ACTING COMPOUNDS AND METHODS FOR THE TREATMENT OF CNS DISORDERS | CLERA INC. (CA) | 2007-08-30 | — | — | WO | disclosed |