Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 17/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.41 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28157735 | 0.78 | MEN1 (0.47) | POLBMEN1LMNAKMT2ASIRT1 | |
| SCHEMBL5924318 | 0.75 | KDM4E (0.44) | POLBMEN1LMNAKMT2ASIRT1 | |
| SCHEMBL5428977 | 0.74 | SIRT1 (0.43) | POLBMEN1LMNAKMT2ASIRT1 | |
| SCHEMBL10397442 | 0.73 | MEN1 (0.60) | POLBMEN1LMNAKMT2ASIRT1 | |
| SCHEMBL8581789 | 0.72 | ALDH1A1 (0.46) | POLBMEN1LMNAKMT2ASIRT1 | |
| SCHEMBL15968071 | 0.71 | RET (0.42) | POLBMEN1LMNAKMT2ASIRT1 | |
| SCHEMBL120709 | 0.71 | MEN1 (0.48) | POLBMEN1LMNAKMT2ASIRT1 | |
| SCHEMBL7379470 | 0.71 | MEN1 (0.48) | POLBMEN1LMNAKMT2ASIRT1 | |
| SCHEMBL2533982 | 0.71 | MAOA (0.42) | POLBMEN1LMNAKMT2ASIRT1 | |
| SCHEMBL8086196 | 0.71 | MAOA (0.42) | POLBMEN1LMNAKMT2ASIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080131381-A1 | METHODS FOR PHOTOSTABILIZING INGREDIENTS WITHIN COSMETICS, PERSONAL CARE AND HOUSEHOLD PRODUCTS AND COMPOSITIONS OBTAINED THEREFROM | MERCK PATENT GESELLSCHAFT (DE) | 2008-06-05 | — | — | US | claimed |
| US-7150876-B2 | Methods for stabilizing ingredients within cosmetics, personal care and household products | MERCK PATENT GMBH (DE) | 2006-12-19 | — | — | US | claimed |
| US-20050244349-A1 | Methods for stabilizing ingredients within cosmetics, personal care and household products | SUSONITY Commercial GmbH (DE) | 2005-11-03 | — | — | US | claimed |
| EP-1591099-A2 | Methods for stabilizing ingredients within cosmetics, personal care and household products | MERCK PATENT GmbH (DE) | 2005-11-02 | — | — | EP | claimed |
| WO-2008083974-A1 | ACTIVE SUBSTANCE COMBINATION | ISDIN S.A. (ES) | 2008-07-17 | — | — | WO | disclosed |
| US-7150876-B2 | Methods for stabilizing ingredients within cosmetics, personal care and household products | MERCK PATENT GMBH (DE) | 2006-12-19 | — | — | US | disclosed |
| US-20050244349-A1 | Methods for stabilizing ingredients within cosmetics, personal care and household products | SUSONITY Commercial GmbH (DE) | 2005-11-03 | — | — | US | disclosed |
| EP-1591099-A2 | Methods for stabilizing ingredients within cosmetics, personal care and household products | MERCK PATENT GmbH (DE) | 2005-11-02 | — | — | EP | disclosed |
| EP-1406582-A1 | PHOTOSTABLE ORGANIC SUNSCREEN COMPOUNDS WITH ANTIOXIDANT PROPERTIES AND COMPOSITIONS OBTAINED THEREFROM | MERCK PATENT GmbH (DE) | 2004-04-14 | — | — | EP | disclosed |
| WO-2003007906-A1 | PHOTOSTABLE ORGANIC SUNSCREEN COMPOUNDS WITH ANTIOXIDANT PROPERTIES AND COMPOSITIONS OBTAINED THEREFROM | MERCK PATENT GMBH (DE) | 2003-01-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050244349-A1 | Methods for stabilizing ingredients within cosmetics, personal care and household products | CUTA, TYR, LAGE3 | POLB 325/4885MEN1 833/4885LMNA 1379/4885 |
| US-20080131381-A1 | METHODS FOR PHOTOSTABILIZING INGREDIENTS WITHIN COSMETICS, PERSONAL CARE AND HOUSEHOLD PRODUCTS AND COMPOSITIONS OBTAINED THEREFROM | TYR, NISCH, PPOX | POLB 698/4885MEN1 1789/4885LMNA 1693/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.