Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | G6PD | P11413 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4787140 | 0.88 | POLB (0.51) | GAAMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL4741026 | 0.84 | ALDH1A1 (0.52) | GAAMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL4795192 | 0.84 | CYP3A4 (0.55) | GAAMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL4740080 | 0.82 | GAA (0.47) | GAALMNAMAPTHTTPOLB | |
| SCHEMBL4740422 | 0.79 | POLB (0.50) | SIRT2GAAMEN1KMT2ALMNA | |
| SCHEMBL4736655 | 0.78 | HSD17B10 (0.47) | GAAMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL4740909 | 0.77 | CYP2C19 (0.46) | GAAMEN1KMT2AALDH1A1USP2 | |
| SCHEMBL4807472 | 0.71 | CYP3A4 (0.50) | GAAMEN1KMT2ALMNAMAPT | |
| SCHEMBL4740406 | 0.71 | ALDH1A1 (0.44) | GAAMEN1KMT2ALMNAHTT | |
| SCHEMBL4739855 | 0.71 | KMT2A (0.58) | GAAMEN1KMT2ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008087654-A2 | PIPERIDINES AS INHIBITORS OF 11β-HYDROXYSTEROID DEHYDROGENASE TYPE 1 | CADILA HEALTHCARE LIMITED (IN) | 2008-07-24 | — | — | WO | disclosed |