Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | USP5 | P45974 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4795192 | 0.93 | CYP3A4 (0.55) | POLBCYP2C19MEN1KMT2AGAA | |
| SCHEMBL4741026 | 0.93 | ALDH1A1 (0.52) | POLBCYP2C19MEN1KMT2AGAA | |
| SCHEMBL4740423 | 0.88 | SIRT2 (0.48) | POLBMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL4740080 | 0.87 | GAA (0.47) | POLBCYP2C19GAAALDH1A1USP2 | |
| SCHEMBL4736655 | 0.85 | HSD17B10 (0.47) | CYP2C19MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL4740909 | 0.84 | CYP2C19 (0.46) | CYP2C19MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL4736817 | 0.79 | HTT (0.46) | POLBKMT2AALDH1A1LMNACYP3A4 | |
| SCHEMBL4740625 | 0.79 | LMNA (0.57) | CYP2C19ALDH1A1LMNASMN1; SMN2CYP3A4 | |
| SCHEMBL4739855 | 0.77 | KMT2A (0.58) | POLBCYP2C19MEN1KMT2AGAA | |
| SCHEMBL4807472 | 0.76 | CYP3A4 (0.50) | POLBCYP2C19MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008087654-A2 | PIPERIDINES AS INHIBITORS OF 11β-HYDROXYSTEROID DEHYDROGENASE TYPE 1 | CADILA HEALTHCARE LIMITED (IN) | 2008-07-24 | — | — | WO | claimed |