Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4787137 | 0.87 | DPP4 (0.49) | MEN1KMT2ALMNAHTTSMN1; SMN2 | |
| SCHEMBL4740078 | 0.80 | GAA (0.50) | LMNAHTTMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL4740423 | 0.79 | SIRT2 (0.48) | POLBSIRT2MEN1KMT2ALMNA | |
| SCHEMBL4738282 | 0.76 | ALDH1A1 (0.50) | POLBMEN1KMT2ALMNAHTT | |
| SCHEMBL4736650 | 0.76 | P2RX7 (0.53) | MEN1KMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL4740908 | 0.75 | P2RX7 (0.49) | LMNAHTTMAPTUSP2GAA | |
| SCHEMBL4737593 | 0.74 | LMNA (0.57) | POLBMEN1KMT2ALMNAHTT | |
| SCHEMBL4736709 | 0.74 | LMNA (0.57) | POLBMEN1KMT2ALMNAHTT | |
| SCHEMBL4741721 | 0.74 | KMT2A (0.50) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL4740625 | 0.73 | LMNA (0.57) | LMNAHTTMAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008087654-A2 | PIPERIDINES AS INHIBITORS OF 11β-HYDROXYSTEROID DEHYDROGENASE TYPE 1 | CADILA HEALTHCARE LIMITED (IN) | 2008-07-24 | — | — | WO | disclosed |