Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 4/20 | 0.56 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.56 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.56 |
| ▸ | CTSL | P07711 | 3/20 | 0.55 |
| ▸ | KYNU | Q16719 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | CTSS | P25774 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CTSK | P43235 | 4/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4740911 | 0.99 | SIRT2 (0.55) | SIRT2SIRT1SIRT3CTSLKYNU | |
| SCHEMBL8064258 | 0.96 | SIRT2 (0.57) | SIRT2SIRT1SIRT3CTSLKYNU | |
| SCHEMBL7320626 | 0.90 | CTSL (0.57) | SIRT2SIRT1CTSLCTSS | |
| SCHEMBL8386880 | 0.88 | SIRT2 (0.67) | SIRT2SIRT1SIRT3CTSLKYNU | |
| SCHEMBL7996588 | 0.88 | CTSL (0.57) | SIRT2SIRT1SIRT3CTSLCTSS | |
| SCHEMBL1345896 | 0.87 | LTA4H (0.55) | CTSLALDH1A1 | |
| SCHEMBL8447229 | 0.86 | SIRT2 (0.59) | SIRT2SIRT1SIRT3CTSLKYNU | |
| SCHEMBL8447232 | 0.86 | SIRT2 (0.59) | SIRT2SIRT1SIRT3CTSLKYNU | |
| Hydrochloric Acid SCHEMBL1347691 | 0.86 | LTA4H (0.54) | CTSLALDH1A1 | |
| Hydrochloric Acid SCHEMBL6236103 | 0.85 | SIRT2 (0.58) | SIRT2SIRT1SIRT3CTSLKYNU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008098096-A1 | ANTI-CYTOKINE HETEROCYCLIC COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-08-14 | — | — | WO | disclosed |