Sugi Predict

Sugi Predict / Compounds / SCHEMBL4740487

SCHEMBL4740487

SCHEMBL4740487

O=C1C(=O)c2ccccc2/C1=C/c1ccccc1

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 5/20 0.60
▸ KMT2A Q03164 5/20 0.60
▸ HPGD P15428 5/20 0.60
▸ MAPT P10636 4/20 0.60
▸ ALDH1A1 P00352 3/20 0.60
▸ TUBB4A P04350 1/20 0.53
▸ TUBB P07437 1/20 0.53
▸ TUBA3C P0DPH7 1/20 0.53
▸ AR P10275 1/20 0.53
▸ TUBA1B P68363 1/20 0.53
▸ TUBA4A P68366 1/20 0.53
▸ TUBB4B P68371 1/20 0.53
▸ TUBB3 Q13509 1/20 0.53
▸ TUBB2A Q13885 1/20 0.53
▸ TUBB8 Q3ZCM7 1/20 0.53
▸ TUBA3E Q6PEY2 1/20 0.53
▸ TUBA1A Q71U36 1/20 0.53
▸ TUBA1C Q9BQE3 1/20 0.53
▸ TUBB6 Q9BUF5 1/20 0.53
▸ TUBB2B Q9BVA1 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30175403 1.00 MEN1 (0.60) MEN1KMT2AHPGDMAPTALDH1A1
SCHEMBL4740488 1.00 MEN1 (0.60) MEN1KMT2AHPGDMAPTALDH1A1
SCHEMBL8778480 0.91 TUBB4A (0.52) MEN1KMT2AHPGDMAPTALDH1A1
SCHEMBL8778476 0.91 TUBB4A (0.52) MEN1KMT2AHPGDMAPTALDH1A1
SCHEMBL4726286 0.89 TUBB4A (0.65) MEN1KMT2AHPGDMAPTALDH1A1
SCHEMBL29491367 0.87 HPGD (0.54) MEN1KMT2AHPGDMAPTALDH1A1
SCHEMBL677432 0.86 MAPT (0.62) MEN1KMT2AHPGDMAPTALDH1A1
SCHEMBL7898058 0.84 CYP1A2 (0.56) MEN1KMT2AHPGDMAPTALDH1A1
SCHEMBL4541307 0.81 CYP19A1 (0.62) MEN1KMT2AHPGDMAPTALDH1A1
SCHEMBL22625286 0.79 LCK (0.66) MEN1KMT2AHPGDMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7166274-B2 Synergistically high SPF photoprotective UV-screening compositions comprising insoluble organic sunscreen particles/diarylbutadiene compounds L'OREAL (FR) 2007-01-23 — — US claimed
US-20040047820-A1 Synergistically high SPF photoprotective UV-screening compositions comprising insoluble organic sunscreen particles/diarylbutadiene compounds SOCIETE L'OREAL S.A. (FR) 2004-03-11 — — US claimed
US-6627180-B2 Particles having protection factor UV-APPD and an amino substituted 2-hydroxybenzophenone SOCIETE L'OREAL S.A. (FR) 2003-09-30 — — US claimed
US-20030152532-A1 SYNERGISTICALLY UV-PHOTOPROTECTING COMPOSITIONS COMPRISING MIXED SCREENING AGENTS SOCIETE L'OREAL S.A. (FR) 2003-08-14 — — US claimed
EP-2872107-B1 COSMETIC COMPOSITION CONTAINING SCREENING COMPOSITE PARTICLES OREAL (FR) 2021-07-21 — — EP disclosed
US-20150190320-A1 COSMETIC COMPOSITION COMPRISING COMPOSITE SUNSCREEN PARTICLES L'OREAL (FR) 2015-07-09 — — US disclosed
US-20150157539-A1 COSMETIC COMPOSITION COMPRISING COMPOSITE PARTICLES L'OREAL (FR) 2015-06-11 — — US disclosed
EP-2872107-A1 COSMETIC COMPOSITION CONTAINING SCREENING COMPOSITE PARTICLES L'Oréal (FR) 2015-05-20 — — EP disclosed
WO-2014009097-A1 COSMETIC COMPOSITION CONTAINING SCREENING COMPOSITE PARTICLES L'OREAL (FR) 2014-01-16 — — WO disclosed
WO-2014010099-A1 COMPOSITE PIGMENT AND METHOD FOR PREPARING THE SAME L'OREAL (FR) 2014-01-16 — — WO disclosed
WO-2014010100-A1 COSMETIC COMPOSITION COMPRISING COMPOSITE SUNSCREEN PARTICLES L'OREAL (FR) 2014-01-16 — — WO disclosed
WO-2014010098-A1 COSMETIC COMPOSITION COMPRISING COMPOSITE PARTICLES L'OREAL (FR) 2014-01-16 — — WO disclosed
WO-2008086928-A1 O/W COSMETIC EMULSION COMPRISING A LIPOPHILIC UV SCREENING AGENT, A POLAR OIL AND A POLYSTYRENE-BLOCK-POLY(ACRYLIC ACID-STAT-C1-C4 ALKYL ACRYLATE) DIBLOCK COPOLYMER L'OREAL (FR) 2008-07-24 — — WO disclosed
US-7166274-B2 Synergistically high SPF photoprotective UV-screening compositions comprising insoluble organic sunscreen particles/diarylbutadiene compounds L'OREAL (FR) 2007-01-23 — — US disclosed
US-20040047820-A1 Synergistically high SPF photoprotective UV-screening compositions comprising insoluble organic sunscreen particles/diarylbutadiene compounds SOCIETE L'OREAL S.A. (FR) 2004-03-11 — — US disclosed
US-6627180-B2 Particles having protection factor UV-APPD and an amino substituted 2-hydroxybenzophenone SOCIETE L'OREAL S.A. (FR) 2003-09-30 — — US disclosed
US-20030152532-A1 SYNERGISTICALLY UV-PHOTOPROTECTING COMPOSITIONS COMPRISING MIXED SCREENING AGENTS SOCIETE L'OREAL S.A. (FR) 2003-08-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040047820-A1 Synergistically high SPF photoprotective UV-screening compositions comprising insoluble organic sunscreen particles/diarylbutadiene compounds SUCLG1, CUTA, DLD MEN1 4027/4885KMT2A 3376/4885HPGD 295/4885
US-20150157539-A1 COSMETIC COMPOSITION COMPRISING COMPOSITE PARTICLES MITF, RAB5IF, TYR MEN1 341/4885KMT2A 3148/4885HPGD 1904/4885
US-20030152532-A1 SYNERGISTICALLY UV-PHOTOPROTECTING COMPOSITIONS COMPRISING MIXED SCREENING AGENTS HADHB, SDHA, ERCC4 MEN1 3716/4885KMT2A 3626/4885HPGD 266/4885
US-20150190320-A1 COSMETIC COMPOSITION COMPRISING COMPOSITE SUNSCREEN PARTICLES XPA, ERCC1, ERCC4 MEN1 866/4885KMT2A 3290/4885HPGD 1542/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.