Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 10/20 | 0.40 |
| ▸ | PTPRA | P18433 | 1/20 | 0.40 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5339338 | 0.85 | ATM (0.44) | ALDH1A1 | |
| SCHEMBL1465488 | 0.78 | SRD5A2 (0.45) | TAS2R14TRPA1TRPM8KDM4EALDH1A1 | |
| SCHEMBL272401 | 0.74 | KIF11 (0.40) | ALDH1A1 | |
| SCHEMBL28610571 | 0.73 | LMNA (0.41) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL504005 | 0.73 | L3MBTL1 (0.55) | ALDH1A1CYP2C19HSD17B10SMN1; SMN2 | |
| SCHEMBL1690946 | 0.73 | ALDH1A1 (0.39) | PTPN1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL29837166 | 0.73 | MT-CO2 (0.41) | PTPN1PTPRA | |
| SCHEMBL21000444 | 0.73 | GSK3B (0.41) | TRPM8CYP2C19SMN1; SMN2 | |
| SCHEMBL7667615 | 0.72 | LMNA (0.49) | SMN1; SMN2 | |
| SCHEMBL5058365 | 0.72 | PTGIR (0.50) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008090357-A2 | N, N; -SUBSTITUTED PIPERAZINES BINDING TO MELANOCORTIN RECEPTOR | PALATIN TECHNOLOGIES, INC. (US) | 2008-07-31 | — | — | WO | disclosed |