Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4743465 | 0.83 | ALDH1A1 (0.56) | LMNAALDH1A1KDM4EHPGDCYP1A2 | |
| SCHEMBL14093129 | 0.80 | ALDH1A1 (0.40) | ALDH1A1KDM4EHPGDCYP1A2CYP3A4 | |
| SCHEMBL14093107 | 0.78 | LMNA (0.48) | LMNAALDH1A1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL14093106 | 0.78 | ALDH1A1 (0.46) | ALDH1A1CYP3A4HTTMEN1KMT2A | |
| SCHEMBL7984370 | 0.75 | TDP1 (0.51) | CACNA2D1LMNAALDH1A1HTTHSD17B10 | |
| SCHEMBL7887739 | 0.73 | PDE7A (0.53) | CACNA2D1ALDH1A1CA12CA1CA2 | |
| SCHEMBL12963478 | 0.69 | MEN1 (0.52) | CACNA2D1ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL14103480 | 0.67 | LMNA (0.48) | LMNAALDH1A1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL14103484 | 0.67 | ALDH1A1 (0.46) | ALDH1A1KDM4ECYP1A2CYP3A4CYP2C9 | |
| SCHEMBL31241088 | 0.66 | CACNA2D1 (0.48) | CACNA2D1ALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008103354-A2 | MODULATORS OF ACETYL-COENZYME A CARBOXYLASE AND METHODS OF USE THEREOF | CROPSOLUTION, INC. (US) | 2008-08-28 | — | — | WO | disclosed |
| US-20080200461-A1 | MODULATORS OF ACETYL-COENZYME A CARBOXYLASE AND METHODS OF USE THEREOF | CROPSOLUTION, INC. | 2008-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200461-A1 | MODULATORS OF ACETYL-COENZYME A CARBOXYLASE AND METHODS OF USE THEREOF | ACACA, ACAT1, ACACB | CACNA2D1 4200/4885LMNA 2455/4885ALDH1A1 702/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.