Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14093106 | 0.91 | ALDH1A1 (0.46) | ALDH1A1NPSR1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL14093129 | 0.84 | ALDH1A1 (0.40) | ALDH1A1NPSR1SMN1; SMN2HSD17B10USP2 | |
| Morpholine SCHEMBL4743469 | 0.83 | CACNA2D1 (0.43) | ALDH1A1KMT2AMEN1HSD17B10USP2 | |
| SCHEMBL14093107 | 0.82 | LMNA (0.48) | ALDH1A1NPSR1KMT2AMEN1LMNA | |
| SCHEMBL14103484 | 0.80 | ALDH1A1 (0.46) | ALDH1A1NPSR1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9960599 | 0.78 | MAPK1 (0.49) | ALDH1A1NPSR1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL14093110 | 0.77 | ALDH1A1 (0.47) | ALDH1A1NPSR1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL14093109 | 0.76 | ALDH1A1 (0.46) | ALDH1A1NPSR1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL2724274 | 0.73 | ALDH1A1 (0.72) | ALDH1A1NPSR1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9953779 | 0.72 | ALOX15 (0.55) | ALDH1A1SMN1; SMN2KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008103354-A2 | MODULATORS OF ACETYL-COENZYME A CARBOXYLASE AND METHODS OF USE THEREOF | CROPSOLUTION, INC. (US) | 2008-08-28 | — | — | WO | disclosed |
| US-20080200461-A1 | MODULATORS OF ACETYL-COENZYME A CARBOXYLASE AND METHODS OF USE THEREOF | CROPSOLUTION, INC. | 2008-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200461-A1 | MODULATORS OF ACETYL-COENZYME A CARBOXYLASE AND METHODS OF USE THEREOF | ACACA, ACAT1, ACACB | ALDH1A1 702/4885NPSR1 2526/4885SMN1; SMN2 4840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.