SCHEMBL474686

SCHEMBL474686

CC(C)(C)NC(=O)C(Cl)(Cl)Cl

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.39
EPHX1 P07099 1/20 0.37
MEN1 O00255 4/20 0.36
KMT2A Q03164 4/20 0.36
POLB P06746 2/20 0.36
APEX1 P27695 1/20 0.36
ALDH1A1 P00352 6/20 0.35
TP53 P04637 1/20 0.35
TSHR P16473 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.32
HTT P42858 2/20 0.32
MAPK1 P28482 3/20 0.31
HPGD P15428 2/20 0.31
KDM4E B2RXH2 1/20 0.31
GLA P06280 1/20 0.31
GAA P10253 1/20 0.31
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31
MAPT P10636 1/20 0.30
NPC1 O15118 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclohexane SCHEMBL27945853 0.92 KDM4E (0.37) L3MBTL1EPHX1MEN1KMT2APOLB
SCHEMBL14680931 0.82 EPHX1 (0.37) L3MBTL1EPHX1MEN1KMT2APOLB
SCHEMBL21306959 0.79 ALDH1A1 (0.39) L3MBTL1EPHX1MEN1KMT2APOLB
SCHEMBL11739867 0.76 ALDH1A1 (0.43) L3MBTL1MEN1KMT2AALDH1A1TP53
SCHEMBL20953659 0.75 MEN1 (0.40) L3MBTL1EPHX1MEN1KMT2APOLB
SCHEMBL153717 0.75 L3MBTL1 (0.42) L3MBTL1EPHX1MEN1KMT2APOLB
SCHEMBL25564484 0.75 MEN1 (0.40) L3MBTL1EPHX1MEN1KMT2APOLB
SCHEMBL13020558 0.74 POLB (0.36) EPHX1MEN1KMT2APOLBAPEX1
SCHEMBL18016462 0.73 ALDH1A1 (0.42) L3MBTL1EPHX1MEN1KMT2APOLB
SCHEMBL10912920 0.72 EPHX1 (0.31) EPHX1POLBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 258 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014055603-A1 PROCESS FOR THE PREPARATION OF AN HIV INTEGRASE INHIBITOR GILEAD SCIENCES, INC. (US) 2014-04-10 WO claimed
EP-2694479-A1 PROCESS FOR THE PREPARATION OF AN HIV INTEGRASE INHIBITOR Gilead Sciences, Inc. (US) 2014-02-12 EP claimed
WO-2012138670-A1 PROCESS FOR THE PREPARATION OF AN HIV INTEGRASE INHIBITOR GILEAD SCIENCES, INC. (US) 2012-10-11 WO claimed
CN-122070279-A Fibroblast activation protein inhibitor 苏州博锐创合医药有限公司 2026-05-19 CN disclosed
CN-116003565-B Preparation method of oligopeptide cyclic peptide 杭州彗搏科技有限公司 2026-05-15 CN disclosed
US-12486241-B2 Cystine diamide analogs for cystinuria RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2025-12-02 US disclosed
EP-4608452-A2 PEPTIDE-ANTISENSE OLIGONUCLEOTIDES AND THEIR USE FOR TREATMENT OF NEURODEGENERATIVE DISORDERS Eisai R&D Management Co., Ltd. (JP) 2025-09-03 EP disclosed
EP-4577537-A1 SUBSTITUTED BICYCLES AS HSET INHIBITORS Merck Patent GmbH (DE) 2025-07-02 EP disclosed
CN-119775349-A Pyroglutamic acid-tetrapeptide-7 derivative and application thereof 云南苏理生物医药科技有限公司 2025-04-08 CN disclosed
CN-119768391-A Indole phthalocyanine compound, preparation method thereof and application thereof in tumor diagnostic imaging 江苏亚虹医药科技股份有限公司 2025-04-04 CN disclosed
CN-119708309-A Narrow distribution copolymer and preparation method and application thereof 上海八亿时空先进材料有限公司 2025-03-28 CN disclosed
US-5578575-A SEPTIC SHOCK ITALFARMACO S.P.A. (IT) 1996-11-26 US disclosed
US-5521159-A Partially modified and retro-inverted tetrapeptides analogues of C-reactive protein fragments ITALFARMACO S.P.A. (IT) 1996-05-28 US disclosed
EP-0701546-A1 AROMATIC ACETYLCHOLINESTERASE INHIBITORS MERRELL PHARMACEUTICALS INC. (US) 1996-03-20 EP disclosed
WO-1994029255-A1 AROMATIC ACETYLCHOLINESTERASE INHIBITORS MERRELL PHARMACEUTICALS INC. (US) 1994-12-22 WO disclosed
EP-0627400-A1 Aromatic acetylcholinesterase inhibitors MERRELL DOW PHARMACEUTICALS INC. (US) 1994-12-07 EP disclosed
WO-1993021208-A1 PARTIALLY MODIFIED AND RETRO-INVERTED TETRAPEPTIDES ANALOGUES OF C-REACTIVE PROTEIN FRAGMENTS ITALFARMACO S.P.A. (IT) 1993-10-28 WO disclosed
US-5196608-A Chemical intermediates for vitamin A DUPHAR INTERNATIONAL RESEARCH B.V. (NL) 1993-03-23 US disclosed
EP-0489454-A1 Use of an allylchloride for preparing an aldehyde DUPHAR INTERNATIONAL RESEARCH B.V (NL) 1992-06-10 EP disclosed
EP-0456287-A1 New sulfonyl compound and use of said compound in the process of producing vitamin A or its esters DUPHAR INTERNATIONAL RESEARCH B.V (NL) 1991-11-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12486241-B2 Cystine diamide analogs for cystinuria CTH, CBS, SLC7A11 L3MBTL1 1772/4885EPHX1 2058/4885MEN1 446/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.