Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.31 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.31 |
| ▸ | TOP1 | P11387 | 1/20 | 0.30 |
| ▸ | KMO | O15229 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.30 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5820441 | 0.79 | ALDH1A1 (0.34) | ALDH1A1CYP1A2GAACYP2C9CYP2C19 | |
| SCHEMBL5819913 | 0.79 | SMN1; SMN2 (0.33) | ALDH1A1CYP1A2GAACYP2C9CYP2C19 | |
| SCHEMBL5814748 | 0.78 | KCNH2 (0.33) | ALDH1A1CYP1A2GAACYP2C9CYP2C19 | |
| SCHEMBL5817989 | 0.68 | NPC1 (0.34) | POLBL3MBTL1ALDH1A1GAATHRB | |
| SCHEMBL5816497 | 0.68 | PSD (0.39) | POLBL3MBTL1ALDH1A1 | |
| SCHEMBL4751098 | 0.63 | GRM2 (0.38) | ALDH1A1CYP1A2GRIN2BKDM1AGRIN1 | |
| SCHEMBL5815540 | 0.63 | KDM4E (0.42) | L3MBTL1ALDH1A1 | |
| SCHEMBL4747881 | 0.62 | — | — | |
| SCHEMBL5820059 | 0.60 | L3MBTL1 (0.46) | POLBL3MBTL1ALDH1A1CYP1A2GAA | |
| SCHEMBL28825549 | 0.58 | GRIN2B (0.40) | ALDH1A1GRIN2BCYP11B1CYP11B2TRPV3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008123755-A1 | A PHARMACEUTICAL COMPOSITIONS CONTAINING LACTAM TYPE PYRIDINE DERIVATIVES AS AN EFFECTIVE INGREDIENT FOR THE PREVENTION AND TREATMENT OF ISCHEMIA | SK CHEMICALS CO., LTD. (KR) | 2008-10-16 | — | — | WO | claimed |