Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA5A | P35218 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27860826 | 0.86 | CA2 (0.39) | CA2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL329981 | 0.73 | NPC1 (0.39) | CA2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL1742332 | 0.69 | NPC1 (0.60) | CA2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL15527912 | 0.64 | ALDH1A1 (0.35) | ALDH1A1HPGD | |
| SCHEMBL13281038 | 0.64 | NPSR1 (0.46) | CA2ALDH1A1MAPK1ATMCA1 | |
| SCHEMBL7802900 | 0.62 | PLA2G7 (0.50) | KDM4EALDH1A1HSD17B10SMN1; SMN2NPSR1 | |
| SCHEMBL3882545 | 0.61 | RAB9A (0.39) | KDM4EALDH1A1HSD17B10PKMSMN1; SMN2 | |
| SCHEMBL8323703 | 0.61 | CA2 (0.38) | CA2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL12967648 | 0.59 | NPC1 (0.40) | KDM4EALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL3427273 | 0.59 | SMN1; SMN2 (0.40) | ALDH1A1HSD17B10MAPK1CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1959964-A1 | HETEROAROMATIC SULFONAMIDE PRODRUGS | Bayer Schering Pharma AG (DE) | 2008-08-27 | — | — | EP | disclosed |
| WO-2007062875-A1 | HETEROAROMATIC SULFONAMIDE PRODRUGS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-06-07 | — | — | WO | disclosed |