Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRA | P11474 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 10/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4103776 | 0.83 | PKM (0.34) | SLC22A12 | |
| SCHEMBL4751336 | 0.79 | RAPGEF4 (0.34) | SLC22A12 | |
| SCHEMBL4751277 | 0.78 | AR (0.40) | ESRRAARSLC22A12MRGPRX4BCAT1 | |
| SCHEMBL4105432 | 0.78 | AR (0.38) | ESRRAARSLC22A12MRGPRX4 | |
| SCHEMBL4109832 | 0.74 | ENPP3 (0.39) | ESRRAARSLC22A12 | |
| SCHEMBL4751257 | 0.71 | P2RY12 (0.37) | ARMRGPRX4NPC1RAB9A | |
| SCHEMBL17156280 | 0.70 | HTR1A (0.45) | CYP19A1 | |
| SCHEMBL16635898 | 0.70 | KDM4E (0.32) | — | |
| SCHEMBL13890508 | 0.69 | AR (0.66) | ARSLC22A12CYP19A1 | |
| SCHEMBL17645458 | 0.69 | TGFBR1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008135824-A1 | OXYALKYLPYRAZOLE COMPOUNDS USEFUL IN THERAPY | PFIZER LIMITED (GB) | 2008-11-13 | — | — | WO | disclosed |