Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 10/20 | 0.40 |
| ▸ | ESRRA | P11474 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | SGK1 | O00141 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | FASN | P49327 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4105432 | 0.88 | AR (0.38) | ARESRRASLC22A12SGK1HRH3 | |
| SCHEMBL4751633 | 0.86 | AR (0.41) | ARESRRASLC22A12 | |
| SCHEMBL4748718 | 0.84 | PKM (0.35) | — | |
| SCHEMBL4751257 | 0.80 | P2RY12 (0.37) | ARMRGPRX4 | |
| SCHEMBL4109832 | 0.80 | ENPP3 (0.39) | ARESRRASLC22A12HRH3DRD1 | |
| SCHEMBL4751664 | 0.80 | RAPGEF4 (0.33) | — | |
| SCHEMBL4748846 | 0.78 | ESRRA (0.41) | ARESRRASLC22A12MRGPRX4BCAT1 | |
| SCHEMBL4105299 | 0.74 | AR (0.41) | ARESRRASLC22A12 | |
| SCHEMBL4105032 | 0.72 | LRRK2 (0.37) | FASN | |
| SCHEMBL4098122 | 0.71 | PGR (0.44) | HRH3FASN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008135824-A1 | OXYALKYLPYRAZOLE COMPOUNDS USEFUL IN THERAPY | PFIZER LIMITED (GB) | 2008-11-13 | — | — | WO | disclosed |