Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | HMGCR | P04035 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | TYMS | P04818 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4749246 | 0.71 | DYRK1A (0.36) | MAOAMAOB | |
| SCHEMBL4786337 | 0.71 | PKM (0.43) | — | |
| SCHEMBL4747016 | 0.69 | MAOA (0.34) | MAOAMAOB | |
| SCHEMBL4786331 | 0.66 | PKM (0.42) | PIK3CD | |
| SCHEMBL4788073 | 0.64 | HSD11B1 (0.41) | — | |
| SCHEMBL4787522 | 0.64 | PKM (0.44) | — | |
| SCHEMBL29112870 | 0.63 | PARP10 (0.50) | TYMSMAOAMAOB | |
| SCHEMBL18238925 | 0.63 | MAOA (0.36) | MAOAMAOB | |
| SCHEMBL29882718 | 0.62 | CA12 (0.43) | CA1CA2CA12CA9 | |
| SCHEMBL3163913 | 0.61 | KDM4E (0.40) | CA1CA2CA12CA9MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008123756-A1 | A PHARMACEUTICAL COMPOSITIONS CONTAINING LACTON TYPE PYRIDINE DERIVATIVES AS AN EFFECTIVE INGREDIENT FOR THE PREVENTION AND TREATMENT OF ISCHEMIA | SK CHEMICALS CO., LTD. (KR) | 2008-10-16 | — | — | WO | claimed |