Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 8/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4745815 | 0.88 | ALOX5 (0.71) | ALOX5MEN1KMT2ANPC1RAB9A | |
| SCHEMBL4749787 | 0.83 | ALOX5 (0.57) | ALOX5MEN1KMT2AL3MBTL1NPC1 | |
| SCHEMBL4749308 | 0.81 | LMNA (0.62) | ALOX5MEN1KMT2AALDH1A1POLB | |
| SCHEMBL4749309 | 0.80 | L3MBTL1 (0.76) | MEN1KMT2AL3MBTL1NPC1RAB9A | |
| SCHEMBL5216830 | 0.80 | MAPT (0.49) | MEN1KMT2AL3MBTL1ALDH1A1POLB | |
| SCHEMBL10904297 | 0.80 | ALOX5 (1.00) | ALOX5MEN1KMT2ANPC1RAB9A | |
| SCHEMBL4748961 | 0.78 | CYP2D6 (0.65) | ALOX5NPC1RAB9AALDH1A1POLB | |
| SCHEMBL4746770 | 0.77 | MEN1 (0.63) | MEN1KMT2AL3MBTL1ALDH1A1POLB | |
| SCHEMBL6404247 | 0.77 | HDAC4 (0.66) | L3MBTL1CYP1A2CYP3A4CYP2C9MAPT | |
| SCHEMBL5218310 | 0.77 | MAPT (0.48) | MEN1KMT2AL3MBTL1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008122667-A2 | UREYLENE DERIVATIVES | SCHOOL OF PHARMACY (GB) | 2008-10-16 | — | — | WO | disclosed |
| WO-2008122667-A2 | UREYLENE DERIVATIVES | SCHOOL OF PHARMACY (GB) | 2008-10-16 | — | — | WO | disclosed |