Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | RHOC | P08134 | 1/20 | 0.32 |
| ▸ | RHOA | P61586 | 1/20 | 0.32 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4752455 | 0.77 | OPRM1 (0.47) | HTR2A | |
| SCHEMBL4750828 | 0.77 | HTR1A (0.51) | HTR2A | |
| SCHEMBL4754005 | 0.76 | DRD2 (0.42) | — | |
| SCHEMBL4750439 | 0.75 | SMN1; SMN2 (0.36) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4817572 | 0.73 | OPRM1 (0.45) | HTR2A | |
| Hydrochloric Acid SCHEMBL4789360 | 0.68 | POLB (0.40) | POLBALDH1A1 | |
| SCHEMBL18649397 | 0.66 | HTR2A (0.49) | POLBHTR2AFFAR4ALDH1A1 | |
| SCHEMBL4790529 | 0.66 | EGFR (0.42) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4752998 | 0.65 | — | — | |
| SCHEMBL11457316 | 0.65 | POLB (0.68) | POLBALDH1A1RHOCRHOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008146064-A1 | NEW BENZOFURAN DERIVATIVES AS SELECTIVE 5HT7 RECEPTOR INHIBITORS AND PROCESS FOR THEIR PREPARATION | EGIS GYÓGYSZERGYÁR (HU) | 2008-12-04 | — | — | WO | disclosed |